hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03034.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHMP3 | Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Neuroendocrine differentiation factor) (Vacuolar protein sorting-associated protein 24) (hVps24) | 5 | UniProt NCBI |
| CHMP5 | Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60) | 5 | UniProt NCBI |
| CHMP1A | Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1186 | 2.80642455698e-08 | 1.0 | CHMP3 CHMP5 CHMP1A | ESCRT-III complex |
| GO:0051469 | 1.15344049292e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | vesicle fusion with vacuole |
| GO:0061763 | 1.15344049292e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body-lysosome fusion |
| GO:1904930 | 1.15344049292e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | amphisome membrane |
| GO:0097576 | 1.58598067776e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | vacuole fusion |
| GO:0044753 | 1.58598067776e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | amphisome |
| GO:0046761 | 2.11464090368e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | viral budding from plasma membrane |
| GO:0097212 | 2.11464090368e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | lysosomal membrane organization |
| KEGG:04217 | 2.18996976196e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | Necroptosis |
| GO:0046753 | 2.74903317479e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | non-lytic viral release |
| GO:0032510 | 3.49876949518e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | endosome to lysosome transport via multivesicular body sorting pathway |
| GO:0061952 | 5.38272230028e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | midbody abscission |
| GO:1901673 | 7.84339535184e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of mitotic spindle assembly |
| GO:1902774 | 7.84339535184e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | late endosome to lysosome transport |
| GO:0005828 | 9.31403198031e-05 | 1.0 | CHMP3 CHMP5 CHMP1A | kinetochore microtubule |
| KEGG:04144 | 0.000105930292769 | 1.0 | CHMP3 CHMP5 CHMP1A | Endocytosis |
| GO:0032585 | 0.000109576846827 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body membrane |
| GO:0039702 | 0.000109576846827 | 1.0 | CHMP3 CHMP5 CHMP1A | viral budding via host ESCRT complex |
| GO:0046755 | 0.000170228592746 | 1.0 | CHMP3 CHMP5 CHMP1A | viral budding |
| GO:0031468 | 0.000194546963139 | 1.0 | CHMP3 CHMP5 CHMP1A | nuclear membrane reassembly |
| GO:0001778 | 0.000194546963139 | 1.0 | CHMP3 CHMP5 CHMP1A | plasma membrane repair |
| GO:1902410 | 0.000194546963139 | 1.0 | CHMP3 CHMP5 CHMP1A | mitotic cytokinetic process |
| GO:0090169 | 0.000221076094476 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of spindle assembly |
| GO:0035891 | 0.000281151120149 | 1.0 | CHMP3 CHMP5 CHMP1A | exit from host cell |
| GO:0019076 | 0.000281151120149 | 1.0 | CHMP3 CHMP5 CHMP1A | viral release from host cell |
| GO:0036258 | 0.000432059584639 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body assembly |
| GO:0045324 | 0.000432059584639 | 1.0 | CHMP3 CHMP5 CHMP1A | late endosome to vacuole transport |
| GO:0036257 | 0.000476755403739 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body organization |
| GO:0019068 | 0.000476755403739 | 1.0 | CHMP3 CHMP5 CHMP1A | virion assembly |
| GO:0043162 | 0.000524430944113 | 1.0 | CHMP3 CHMP5 CHMP1A | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| GO:0000421 | 0.000524430944113 | 1.0 | CHMP3 CHMP5 CHMP1A | autophagosome membrane |
| GO:0032509 | 0.000575182325801 | 1.0 | CHMP3 CHMP5 CHMP1A | endosome transport via multivesicular body sorting pathway |
| GO:0060236 | 0.000629105668845 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of mitotic spindle organization |
| GO:0032506 | 0.000746852719164 | 1.0 | CHMP3 CHMP5 CHMP1A | cytokinetic process |
| GO:0090224 | 0.000746852719164 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of spindle organization |
| GO:0010824 | 0.000810868666521 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of centrosome duplication |
| GO:0071985 | 0.000949666005835 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body sorting pathway |
| GO:0071763 | 0.000949666005835 | 1.0 | CHMP3 CHMP5 CHMP1A | nuclear membrane organization |
| GO:0090148 | 0.00102463963787 | 1.0 | CHMP3 CHMP5 CHMP1A | membrane fission |
| GO:0046605 | 0.00110345807156 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of centrosome cycle |
| GO:0005771 | 0.00145910222354 | 1.0 | CHMP3 CHMP5 CHMP1A | multivesicular body |
| GO:0006998 | 0.00166249223046 | 1.0 | CHMP3 CHMP5 CHMP1A | nuclear envelope organization |
| GO:0071709 | 0.00177091563679 | 1.0 | CHMP3 CHMP5 CHMP1A | membrane assembly |
| GO:0097352 | 0.00177091563679 | 1.0 | CHMP3 CHMP5 CHMP1A | autophagosome maturation |
| GO:0044091 | 0.00212425290779 | 1.0 | CHMP3 CHMP5 CHMP1A | membrane biogenesis |
| REAC:R-HSA-162588 | 0.00239054881557 | 0.666666666667 | CHMP3 CHMP5 | Budding and maturation of HIV virion |
| GO:0008333 | 0.00266444753864 | 1.0 | CHMP3 CHMP5 CHMP1A | endosome to lysosome transport |
| GO:0007080 | 0.0028124724019 | 1.0 | CHMP3 CHMP5 CHMP1A | mitotic metaphase chromosome alignment |
| REAC:R-HSA-917729 | 0.00296224002415 | 0.666666666667 | CHMP3 CHMP5 | Endosomal Sorting Complex Required For Transport (ESCRT) |
| GO:0090307 | 0.00345936027834 | 1.0 | CHMP3 CHMP5 CHMP1A | mitotic spindle assembly |
| GO:0051298 | 0.00419852339422 | 1.0 | CHMP3 CHMP5 CHMP1A | centrosome duplication |
| GO:0005876 | 0.00623088554274 | 1.0 | CHMP3 CHMP5 CHMP1A | spindle microtubule |
| GO:0005776 | 0.00675723888767 | 1.0 | CHMP3 CHMP5 CHMP1A | autophagosome |
| GO:0031902 | 0.00760107672828 | 1.0 | CHMP3 CHMP5 CHMP1A | late endosome membrane |
| GO:0000281 | 0.00789722257484 | 1.0 | CHMP3 CHMP5 CHMP1A | mitotic cytokinesis |
| GO:0007032 | 0.00820096190464 | 1.0 | CHMP3 CHMP5 CHMP1A | endosome organization |
| GO:0080171 | 0.00851239083773 | 1.0 | CHMP3 CHMP5 CHMP1A | lytic vacuole organization |
| GO:0007040 | 0.00851239083773 | 1.0 | CHMP3 CHMP5 CHMP1A | lysosome organization |
| GO:0005643 | 0.00883160549414 | 1.0 | CHMP3 CHMP5 CHMP1A | nuclear pore |
| GO:0006906 | 0.0112921824257 | 1.0 | CHMP3 CHMP5 CHMP1A | vesicle fusion |
| GO:0051310 | 0.0116771431902 | 1.0 | CHMP3 CHMP5 CHMP1A | metaphase chromosome alignment |
| GO:0090174 | 0.0120707547584 | 1.0 | CHMP3 CHMP5 CHMP1A | organelle membrane fusion |
| GO:0051303 | 0.0128843147861 | 1.0 | CHMP3 CHMP5 CHMP1A | establishment of chromosome localization |
| GO:0050000 | 0.0150763323228 | 1.0 | CHMP3 CHMP5 CHMP1A | chromosome localization |
| GO:0061640 | 0.0165038110528 | 1.0 | CHMP3 CHMP5 CHMP1A | cytoskeleton-dependent cytokinesis |
| GO:0051225 | 0.0165038110528 | 1.0 | CHMP3 CHMP5 CHMP1A | spindle assembly |
| GO:0007009 | 0.0180186629002 | 1.0 | CHMP3 CHMP5 CHMP1A | plasma membrane organization |
| GO:0007041 | 0.0185434783245 | 1.0 | CHMP3 CHMP5 CHMP1A | lysosomal transport |
| GO:0006997 | 0.0190783863531 | 1.0 | CHMP3 CHMP5 CHMP1A | nucleus organization |
| GO:0007052 | 0.0225051619375 | 1.0 | CHMP3 CHMP5 CHMP1A | mitotic spindle organization |
| GO:0051701 | 0.0231134095574 | 1.0 | CHMP3 CHMP5 CHMP1A | biological process involved in interaction with host |
| GO:0007098 | 0.025655976884 | 1.0 | CHMP3 CHMP5 CHMP1A | centrosome cycle |
| REAC:R-HSA-9824446 | 0.0269033233908 | 1.0 | CHMP3 CHMP5 CHMP1A | Viral Infection Pathways |
| GO:0048284 | 0.0283784809274 | 1.0 | CHMP3 CHMP5 CHMP1A | organelle fusion |
| REAC:R-HSA-9610379 | 0.0329299631783 | 0.666666666667 | CHMP3 CHMP1A | HCMV Late Events |
| GO:0061025 | 0.0335943388364 | 1.0 | CHMP3 CHMP5 CHMP1A | membrane fusion |
| GO:0070507 | 0.0343879058955 | 1.0 | CHMP3 CHMP5 CHMP1A | regulation of microtubule cytoskeleton organization |
| GO:0007034 | 0.0360123345897 | 1.0 | CHMP3 CHMP5 CHMP1A | vacuolar transport |
| GO:0031023 | 0.0376871301854 | 1.0 | CHMP3 CHMP5 CHMP1A | microtubule organizing center organization |
| GO:0000776 | 0.0402954436201 | 1.0 | CHMP3 CHMP5 CHMP1A | kinetochore |
| GO:1902850 | 0.043021407985 | 1.0 | CHMP3 CHMP5 CHMP1A | microtubule cytoskeleton organization involved in mitosis |
| GO:0000779 | 0.0439566559847 | 1.0 | CHMP3 CHMP5 CHMP1A | condensed chromosome, centromeric region |
| REAC:R-HSA-5663205 | 0.0499835710674 | 1.0 | CHMP3 CHMP5 CHMP1A | Infectious disease |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CHMP5 | CHMP1A | 0.998 | 0.192 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHMP3 | CHMP1A | 0.994 | 0.094 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| CHMP3 | CHMP5 | 0.992 | 0.04 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes