hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03044.1
Complex Portal: CPX-11845
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXP4 | Forkhead box protein P4 (Fork head-related protein-like A) | 5 | UniProt   NCBI |
| FOXP3 | Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form] | 5 | UniProt   NCBI |
| FOXP2 | Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein) | 5 | UniProt   NCBI |
| FOXP1 | Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0001227 | 0.00141370780409 | 1.0 | FOXP4 FOXP1 FOXP3 FOXP2 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
|   GO:0001217 | 0.0017020312212 | 1.0 | FOXP4 FOXP1 FOXP3 FOXP2 | DNA-binding transcription repressor activity |
|   HP:0100326 | 0.00463159007288 | 0.75 | FOXP2 FOXP3 FOXP1 | Immunologic hypersensitivity |
|   HP:0000805 | 0.00844485194452 | 0.5 | FOXP2 FOXP1 | Enuresis |
|   HP:0007301 | 0.0092117244708 | 0.5 | FOXP2 FOXP1 | Oromotor apraxia |
|   HP:0011098 | 0.0135443934278 | 0.5 | FOXP2 FOXP1 | Speech apraxia |
|   HP:0012393 | 0.0135443934278 | 0.5 | FOXP3 FOXP1 | Allergy |
|   HP:0001212 | 0.0259951101914 | 0.5 | FOXP2 FOXP1 | Prominent fingertip pads |
|   HP:0011298 | 0.028689358225 | 0.5 | FOXP2 FOXP1 | Prominent digit pad |
|   HP:0002474 | 0.040788355352 | 0.5 | FOXP2 FOXP1 | Expressive language delay |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  FOXP2 |  FOXP1 | 1.0 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  FOXP3 |  FOXP1 | 1.0 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  FOXP4 |  FOXP2 | 1.0 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  FOXP4 |  FOXP3 | 0.999 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  FOXP3 |  FOXP2 | 0.994 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  FOXP4 |  FOXP1 | 0.722 | 0.164           |          | bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| FOXP4 | huMAP3_00423.1 huMAP3_03044.1 huMAP3_06754.1 |
| FOXP3 | huMAP3_00423.1 huMAP3_02762.1 huMAP3_03044.1 |
| FOXP2 | huMAP3_00423.1 huMAP3_02762.1 huMAP3_03044.1 |
| FOXP1 | huMAP3_02762.1 huMAP3_03044.1 huMAP3_13576.1 |