hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03051.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC25A22 | Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22) | 5 | UniProt NCBI |
| LAMA1 | Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha) | 5 | UniProt NCBI |
| NDUFA4 | Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit) | 5 | UniProt NCBI |
| SLC25A18 | Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428643 | 0.000102258192243 | 0.666666666667 | SLC25A22 SLC25A18 | Organic anion transporters |
| GO:0005280 | 0.00842684400117 | 0.666666666667 | SLC25A22 SLC25A18 | amino acid:proton symporter activity |
| GO:0043490 | 0.00842684400117 | 0.666666666667 | SLC25A22 SLC25A18 | malate-aspartate shuttle |
| GO:0022904 | 0.0116771431902 | 1.0 | SLC25A22 NDUFA4 SLC25A18 | respiratory electron transport chain |
| REAC:R-HSA-425393 | 0.0137071284674 | 0.666666666667 | SLC25A22 SLC25A18 | Transport of inorganic cations/anions and amino acids/oligopeptides |
| GO:0022900 | 0.0150763323228 | 1.0 | SLC25A22 NDUFA4 SLC25A18 | electron transport chain |
| GO:0005313 | 0.0393180950424 | 0.666666666667 | SLC25A22 SLC25A18 | L-glutamate transmembrane transporter activity |
| GO:0015183 | 0.0393180950424 | 0.666666666667 | SLC25A22 SLC25A18 | L-aspartate transmembrane transporter activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC25A22 | LAMA1 | 0.99 | 0.04 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| SLC25A22 | NDUFA4 | 0.989 | 0.092 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| SLC25A22 | SLC25A18 | 0.954 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LAMA1 | NDUFA4 | 0.113 | 0.068 | hein_WMM bioplex3_WMM WMM_only boldt_WMM |
| LAMA1 | SLC25A18 | 0.003 | bioplex3_WMM WMM_only | |
| NDUFA4 | SLC25A18 | 0.001 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SLC25A22 | huMAP3_00885.1 huMAP3_03051.1 huMAP3_11643.1 |
| LAMA1 | huMAP3_00885.1 huMAP3_01090.1 huMAP3_03051.1 huMAP3_11101.1 huMAP3_14233.1 |
| NDUFA4 | huMAP3_01081.1 huMAP3_02111.1 huMAP3_02189.1 huMAP3_03051.1 huMAP3_04679.1 huMAP3_07150.1 huMAP3_09545.1 huMAP3_09939.1 |
| SLC25A18 | huMAP3_03051.1 huMAP3_11643.1 |