hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03059.1
Complex Portal: CPX-13061
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBL3 | Transducin beta-like protein 3 (WD repeat-containing protein SAZD) | 5 | UniProt NCBI |
| NOP2 | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) | 5 | UniProt NCBI |
| TOP2A | DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 0.00292369135789 | 1.0 | TBL3 NOP2 | rRNA modification in the nucleus and cytosol |
| HPA:0091032 | 0.00699773518397 | 1.0 | TBL3 NOP2 | cerebellum; processes in molecular layer[>=Medium] |
| HPA:0091031 | 0.00794557083195 | 1.0 | TBL3 NOP2 | cerebellum; processes in molecular layer[>=Low] |
| REAC:R-HSA-8868773 | 0.0306808172595 | 1.0 | TBL3 NOP2 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.0340043588674 | 1.0 | TBL3 NOP2 | rRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NOP2 | TOP2A | 0.976 | 0.202 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| TBL3 | NOP2 | 0.969 | 0.54 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| TBL3 | TOP2A | 0.965 | 0.206 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| TBL3 | huMAP3_03059.1 huMAP3_13459.1 |
| NOP2 | huMAP3_03059.1 |
| TOP2A | huMAP3_03059.1 huMAP3_05334.1 huMAP3_07289.1 huMAP3_09518.1 huMAP3_15083.1 |