hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_03067.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
ARHGAP8	Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8)	5	UniProt NCBI
PRR5-ARHGAP8	PRR5-ARHGAP8 readthrough	2	UniProt NCBI
SH3GL1	Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)	5	UniProt NCBI
SH3GL2	Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)	5	UniProt NCBI
SH3GL3	Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)	5	UniProt NCBI

Showing 1 to 5 of 5 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8875360	1.13468173222e-06	0.6	SH3GL1 SH3GL2 SH3GL3	InlB-mediated entry of Listeria monocytogenes into host cell
REAC:R-HSA-8876384	3.01907146066e-06	0.6	SH3GL1 SH3GL2 SH3GL3	Listeria monocytogenes entry into host cells
REAC:R-HSA-6807004	3.55148388129e-06	0.6	SH3GL1 SH3GL2 SH3GL3	Negative regulation of MET activity
REAC:R-HSA-182971	9.10580767182e-06	0.6	SH3GL1 SH3GL2 SH3GL3	EGFR downregulation
GO:0016191	1.92180881975e-05	0.6	SH3GL1 SH3GL2 SH3GL3	synaptic vesicle uncoating
GO:0072318	3.362820138e-05	0.6	SH3GL1 SH3GL2 SH3GL3	clathrin coat disassembly
REAC:R-HSA-177929	4.1157848778e-05	0.6	SH3GL1 SH3GL2 SH3GL3	Signaling by EGFR
GO:0072319	5.37995977657e-05	0.6	SH3GL1 SH3GL2 SH3GL3	vesicle uncoating
REAC:R-HSA-9824439	0.000100871107769	0.6	SH3GL1 SH3GL2 SH3GL3	Bacterial Infection Pathways
REAC:R-HSA-6806834	0.00016240432487	0.6	SH3GL1 SH3GL2 SH3GL3	Signaling by MET

Showing 1 to 10 of 20 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
SH3GL1	SH3GL3	1.0	0.194	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
SH3GL2	SH3GL3	1.0	0.206	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
SH3GL1	SH3GL2	1.0	0.144	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
SH3GL3	ARHGAP8	0.839		bioplex () bioplex_WMM bioplex3_WMM
SH3GL2	ARHGAP8	0.763		bioplex () bioplex_WMM bioplex3_WMM
SH3GL1	ARHGAP8	0.485		bioplex () bioplex_WMM bioplex3_WMM youn_WMM

Showing 1 to 6 of 6 entries

Related Complexes

Genename	Complexes
SH3GL1	huMAP3_03067.1 huMAP3_14074.1
SH3GL2	huMAP3_03067.1 huMAP3_14074.1
PRR5-ARHGAP8	huMAP3_03067.1 huMAP3_06394.1 huMAP3_14074.1
SH3GL3	huMAP3_03067.1 huMAP3_14074.1
ARHGAP8	huMAP3_03067.1 huMAP3_14074.1