hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03071.1
Complex Portal: CPX-12256
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZMYND19 | Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein) | 5 | UniProt NCBI |
| WNT10A | Protein Wnt-10a | 5 | UniProt NCBI |
| RMND5B | E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B) | 5 | UniProt NCBI |
| GID4 | Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog) | 5 | UniProt NCBI |
| SFRP2 | Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) | 5 | UniProt NCBI |
| GCG | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4352 | 0.00400681842466 | 0.5 | RMND5B ZMYND19 GID4 | Ciliary landscape |
| WP:WP4336 | 0.0268597929621 | 0.333333333333 | WNT10A SFRP2 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| WP:WP4258 | 0.0337850948883 | 0.333333333333 | WNT10A SFRP2 | lncRNA in canonical Wnt signaling and colorectal cancer |
| WP:WP428 | 0.049971715525 | 0.333333333333 | WNT10A SFRP2 | Wnt signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZMYND19 | GCG | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RMND5B | GCG | 0.993 |
structurally_consistent (Q9H871)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZMYND19 | GID4 | 0.993 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | ||
| RMND5B | GID4 | 0.993 | 0.084 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ZMYND19 | RMND5B | 0.987 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| WNT10A | RMND5B | 0.984 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| WNT10A | ZMYND19 | 0.983 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ZMYND19 | SFRP2 | 0.974 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GID4 | GCG | 0.958 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| WNT10A | GID4 | 0.921 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GID4 | SFRP2 | 0.189 |
mutually_exclusive (Q8IUR7)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
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