hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03079.1
Complex Portal: CPX-22340
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC16A8 | Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8) | 5 | UniProt NCBI |
| NTHL1 | Endonuclease III-like protein 1 (hNTH1) (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycosylase/AP lyase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9616333 | 0.0249718442457 | 0.5 | NTHL1 | Defective Base Excision Repair Associated with NTHL1 |
| REAC:R-HSA-9630222 | 0.0249718442457 | 0.5 | NTHL1 | Defective NTHL1 substrate binding |
| REAC:R-HSA-9630221 | 0.0249718442457 | 0.5 | NTHL1 | Defective NTHL1 substrate processing |
| HPA:0411283 | 0.0263823282362 | 0.5 | SLC16A8 | retina; pigment epithelial cells[High] |
| HPA:0411281 | 0.0351752340474 | 0.5 | SLC16A8 | retina; pigment epithelial cells[>=Low] |
| HPA:0411282 | 0.0351752340474 | 0.5 | SLC16A8 | retina; pigment epithelial cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC16A8 | NTHL1 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SLC16A8 | huMAP3_03079.1 huMAP3_13212.1 |
| NTHL1 | huMAP3_03079.1 huMAP3_13212.1 |