hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03081.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZDHHC5 | Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375) | 5 | UniProt NCBI |
| ZDHHC8 | Palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378) | 5 | UniProt NCBI |
| CLDND1 | Claudin domain-containing protein 1 (Membrane protein GENX-3745) | 4 | UniProt NCBI |
| GOLGA7 | Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa) | 5 | UniProt NCBI |
| L1TD1 | LINE-1 type transposase domain-containing protein 1 (ES cell-associated protein 11) | 4 | UniProt NCBI |
| GOLGA7B | Golgin subfamily A member 7B | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9694548 | 4.60302232639e-05 | 0.5 | GOLGA7 ZDHHC5 ZDHHC8 | Maturation of spike protein |
| REAC:R-HSA-9694635 | 0.00016429546397 | 0.5 | GOLGA7 ZDHHC5 ZDHHC8 | Translation of Structural Proteins |
| REAC:R-HSA-9772573 | 0.000264877822759 | 0.5 | GOLGA7 ZDHHC5 ZDHHC8 | Late SARS-CoV-2 Infection Events |
| GO:0018345 | 0.00185822071527 | 0.5 | GOLGA7 ZDHHC5 ZDHHC8 | protein palmitoylation |
| REAC:R-HSA-9694516 | 0.0227330941007 | 0.5 | GOLGA7 ZDHHC5 ZDHHC8 | SARS-CoV-2 Infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ZDHHC5 | CLDND1 | 1.0 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| GOLGA7 | CLDND1 | 0.999 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ZDHHC8 | CLDND1 | 0.999 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| ZDHHC5 | GOLGA7B | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CLDND1 | GOLGA7B | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CLDND1 | L1TD1 | 0.987 | 0.04 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZDHHC8 | ZDHHC5 | 0.974 | 0.056 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| GOLGA7 | ZDHHC5 | 0.971 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| ZDHHC8 | GOLGA7 | 0.967 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
| ZDHHC8 | GOLGA7B | 0.902 | bioplex3_WMM WMM_only | |
| L1TD1 | GOLGA7B | 0.902 | bioplex3_WMM WMM_only | |
| ZDHHC8 | L1TD1 | 0.902 | 0.064 | bioplex3_WMM WMM_only |
| GOLGA7 | GOLGA7B | 0.73 | bioplex3_WMM WMM_only | |
| ZDHHC5 | L1TD1 | 0.73 | 0.062 | bioplex3_WMM WMM_only |
| GOLGA7 | L1TD1 | 0.388 | 0.046 | bioplex3_WMM WMM_only |
Related Complexes