hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03084.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCAPH | Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog) | 5 | UniProt NCBI |
| GPR137B | Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein) | 5 | UniProt NCBI |
| NCAPD3 | Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) | 5 | UniProt NCBI |
| NCAPG2 | Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2) | 5 | UniProt NCBI |
| SMC2 | Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | 5 | UniProt NCBI |
| SMC4 | Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) | 5 | UniProt NCBI |
| NCAPG | Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) | 5 | UniProt NCBI |
| NCAPD2 | Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000796 | 1.13393166733e-19 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | condensin complex |
| GO:1905821 | 1.13393166733e-19 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of chromosome condensation |
| GO:0060623 | 1.70069372575e-18 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of chromosome condensation |
| CORUM:167 | 9.2015673155e-16 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Condensin I complex |
| CORUM:157 | 9.2015673155e-16 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Condensin I complex |
| CORUM:10 | 9.2015673155e-16 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Condensin I complex |
| CORUM:159 | 5.51999566986e-15 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Condensin I-PARP-1-XRCC1 complex |
| GO:0051984 | 1.67626491379e-14 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of chromosome segregation |
| GO:1905820 | 1.67626491379e-14 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of chromosome separation |
| GO:0030261 | 2.88176985852e-14 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | chromosome condensation |
| GO:0007076 | 5.17676792254e-13 | 0.75 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH | mitotic chromosome condensation |
| GO:0000794 | 7.56939677938e-13 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | condensed nuclear chromosome |
| REAC:R-HSA-2514853 | 9.9030847038e-13 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Condensation of Prometaphase Chromosomes |
| GO:1905818 | 1.10003230817e-11 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of chromosome separation |
| CORUM:160 | 1.68018318789e-11 | 0.5 | SMC2 NCAPD3 SMC4 NCAPG2 | Condensin II |
| GO:0051304 | 2.08000229037e-11 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | chromosome separation |
| GO:2001252 | 3.20739262971e-10 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of chromosome organization |
| GO:0051983 | 7.88720233391e-10 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of chromosome segregation |
| GO:0000070 | 6.84579196878e-09 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | mitotic sister chromatid segregation |
| GO:0000228 | 1.14204846201e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | nuclear chromosome |
| REAC:R-HSA-68886 | 1.43980082161e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | M Phase |
| GO:0090068 | 1.91155517895e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of cell cycle process |
| GO:0000819 | 3.19999568055e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | sister chromatid segregation |
| GO:0000793 | 3.68263860098e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | condensed chromosome |
| GO:0140014 | 7.60973359611e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | mitotic nuclear division |
| GO:0033044 | 8.88490580657e-08 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of chromosome organization |
| GO:0098813 | 1.23485108227e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | nuclear chromosome segregation |
| REAC:R-HSA-69278 | 1.24107692715e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | Cell Cycle, Mitotic |
| GO:0045787 | 1.27140077394e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of cell cycle |
| REAC:R-HSA-1640170 | 5.28730863704e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | Cell Cycle |
| GO:0000280 | 7.94374018339e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | nuclear division |
| GO:0007059 | 9.47946293619e-07 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | chromosome segregation |
| GO:0048285 | 1.80746944526e-06 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | organelle fission |
| GO:0010638 | 3.70311204771e-06 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of organelle organization |
| REAC:R-HSA-2299718 | 3.77533248937e-06 | 0.5 | SMC2 NCAPD3 SMC4 NCAPG2 | Condensation of Prophase Chromosomes |
| REAC:R-HSA-68877 | 4.63370413211e-06 | 0.625 | SMC2 NCAPD2 NCAPH NCAPG SMC4 | Mitotic Prometaphase |
| GO:0051276 | 2.10232693045e-05 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | chromosome organization |
| CORUM:5239 | 2.39226645298e-05 | 0.25 | SMC2 SMC4 | CAP(C)-CAP(E) complex |
| GO:0010564 | 4.14161940848e-05 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of cell cycle process |
| REAC:R-HSA-68875 | 6.70810928111e-05 | 0.5 | SMC2 NCAPD3 SMC4 NCAPG2 | Mitotic Prophase |
| GO:1903047 | 7.16211290092e-05 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | mitotic cell cycle process |
| CORUM:353 | 7.17483486175e-05 | 0.25 | SMC2 SMC4 | DNA ligase IV-condensin complex |
| GO:0000278 | 0.000270004578232 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | mitotic cell cycle |
| GO:0051130 | 0.000415331007079 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | positive regulation of cellular component organization |
| CORUM:49 | 0.000501688733948 | 0.25 | SMC2 SMC4 | DNMT3B complex |
| GO:0051726 | 0.000639086653122 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of cell cycle |
| GO:0033043 | 0.00122469069986 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | regulation of organelle organization |
| GO:0022402 | 0.0022504485569 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | cell cycle process |
| GO:0007049 | 0.0126175578883 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | cell cycle |
| GO:0005694 | 0.0263739534621 | 0.875 | NCAPD3 NCAPG SMC2 SMC4 NCAPD2 NCAPH NCAPG2 | chromosome |
| GO:0010032 | 0.0393180950424 | 0.25 | NCAPD3 NCAPD2 | meiotic chromosome condensation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NCAPD3 | NCAPG2 | 1.0 | 0.598 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () Malo fraction |
| SMC2 | SMC4 | 0.999 | 0.926 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NCAPH | NCAPG | 0.999 | 0.954 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo gupta_WMM fraction |
| NCAPG2 | SMC4 | 0.999 | 0.224 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () fraction boldt_WMM |
| NCAPH | NCAPD2 | 0.998 | 0.944 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo fraction boldt_WMM |
| NCAPG | NCAPD2 | 0.998 | 0.964 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| NCAPG2 | SMC2 | 0.997 | 0.19 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () fraction boldt_WMM |
| NCAPD3 | SMC4 | 0.993 | 0.16 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () fraction treiber_WMM |
| SMC2 | NCAPG | 0.991 | 0.912 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NCAPG2 | NCAPG | 0.991 | 0.194 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| NCAPD3 | SMC2 | 0.99 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () fraction |
| NCAPD3 | NCAPG | 0.987 | 0.224 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NCAPH | NCAPD3 | 0.986 | 0.12 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NCAPH | SMC4 | 0.985 | 0.86 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction boldt_WMM |
| NCAPH | NCAPG2 | 0.983 | 0.162 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NCAPH | SMC2 | 0.981 | 0.84 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction boldt_WMM |
| SMC2 | NCAPD2 | 0.981 | 0.93 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
| SMC4 | NCAPD2 | 0.977 | 0.95 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () fraction boldt_WMM treiber_WMM |
| SMC4 | NCAPG | 0.974 | 0.916 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM fraction boldt_WMM treiber_WMM |
| NCAPD3 | NCAPD2 | 0.96 | 0.158 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM |
| GPR137B | SMC4 | 0.957 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NCAPH | GPR137B | 0.928 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NCAPG2 | NCAPD2 | 0.911 | 0.116 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| GPR137B | NCAPD2 | 0.828 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GPR137B | SMC2 | 0.78 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GPR137B | NCAPG | 0.367 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes