hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03091.1
Complex Portal: CPX-22640
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DPP3 | Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) | 5 | UniProt NCBI |
| RGS19 | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) | 5 | UniProt NCBI |
| TTC7B | Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1) | 5 | UniProt NCBI |
| METTL26 | Methyltransferase-like 26 | 3 | UniProt NCBI |
| RGS20 | Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-418597 | 0.00900400267976 | 0.4 | RGS19 RGS20 | G alpha (z) signalling events |
| WP:WP536 | 0.0360146352745 | 0.4 | RGS19 RGS20 | Calcium regulation in cardiac cells |
| WP:WP289 | 0.0492060648012 | 0.4 | RGS19 RGS20 | Myometrial relaxation and contraction pathways |
| CORUM:6211 | 0.0498708842806 | 0.2 | RGS20 | RSG20-MT1-MT2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RGS19 | RGS20 | 0.993 | 0.17 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| METTL26 | RGS20 | 0.984 | 0.056 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DPP3 | RGS20 | 0.981 | 0.118 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TTC7B | RGS20 | 0.966 | 0.178 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DPP3 | METTL26 | 0.283 | 0.078 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DPP3 | TTC7B | 0.259 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | METTL26 | 0.146 | 0.054 | bioplex3_WMM WMM_only | |
| TTC7B | METTL26 | 0.113 | 0.048 | bioplex3_WMM WMM_only | |
| DPP3 | RGS19 | 0.059 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | TTC7B | 0.053 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes