hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03117.1
Complex Portal: CPX-21269
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CLPP | ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp) | 5 | UniProt NCBI |
| ALDH1A2 | Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (ALDH1A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)) | 5 | UniProt NCBI |
| ALDH2 | Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3996 | 0.000427669224246 | 0.666666666667 | ALDH1A2 ALDH2 | Ethanol effects on histone modifications |
| CORUM:3988 | 0.0249718442456 | 0.333333333333 | CLPP | ClpP complex, heptameric |
| WP:WP4966 | 0.0496447587094 | 0.333333333333 | ALDH2 | Fluoroacetic acid toxicity |
| CORUM:3992 | 0.0499402709677 | 0.333333333333 | CLPP | ClpXP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALDH1A2 | ALDH2 | 0.97 | 0.206 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CLPP | ALDH2 | 0.967 | 0.212 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| CLPP | ALDH1A2 | 0.001 | 0.12 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes