hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03129.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DYNLT4 | Dynein light chain Tctex-type 4 (Protein N22.1) (Tctex-2-beta) (Tctex1 domain-containing protein 4) | 5 | UniProt NCBI |
| LETM2 | LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like) | 3 | UniProt NCBI |
| DYNLT2B | Dynein light chain Tctex-type protein 2B (Tctex1 domain-containing protein 2) | 5 | UniProt NCBI |
| DYNC2I1 | Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010454 | 0.000334337547576 | 0.5 | DYNLT2B DYNC2I1 | Acetabular spurs |
| CORUM:6236 | 0.000338026191524 | 0.5 | DYNLT2B DYNC2I1 | Dynein-2 complex, cytoplasmic |
| GO:0005868 | 0.000510886175237 | 0.75 | DYNLT2B DYNLT4 DYNC2I1 | cytoplasmic dynein complex |
| WP:WP4532 | 0.000894348084449 | 0.5 | DYNLT2B DYNC2I1 | Intraflagellar transport proteins binding to dynein |
| GO:0030286 | 0.00209449363787 | 0.75 | DYNLT2B DYNLT4 DYNC2I1 | dynein complex |
| HP:0000895 | 0.00303997345979 | 0.5 | DYNLT2B DYNC2I1 | Lateral clavicle hook |
| WP:WP4906 | 0.00405547408869 | 0.5 | DYNLT2B DYNC2I1 | 3q29 copy number variation syndrome |
| WP:WP5234 | 0.00722934152515 | 0.5 | DYNLT2B DYNC2I1 | Bardet Biedl syndrome |
| GO:0031021 | 0.00842684400117 | 0.5 | DYNLT2B DYNC2I1 | interphase microtubule organizing center |
| WP:WP4536 | 0.0120322522645 | 0.5 | DYNLT2B DYNC2I1 | Genes related to primary cilium development based on CRISPR |
| REAC:R-HSA-5620924 | 0.0130136556072 | 0.5 | DYNLT2B DYNC2I1 | Intraflagellar transport |
| WP:WP4803 | 0.030443565418 | 0.5 | DYNLT2B DYNC2I1 | Ciliopathies |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DYNC2I1 | DYNLT2B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | |
| DYNLT2B | DYNLT4 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LETM2 | DYNLT2B | 0.982 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DYNC2I1 | DYNLT4 | 0.717 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes