hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03151.1
Complex Portal: CPX-22995
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| F9 | Coagulation factor IX (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain] | 5 | UniProt NCBI |
| LMLN | Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9673218 | 0.0249718442457 | 0.5 | F9 | Defective F9 secretion |
| REAC:R-HSA-9673202 | 0.0499419797295 | 0.5 | F9 | Defective F9 variant does not activate FX |
| REAC:R-HSA-9672396 | 0.0499419797295 | 0.5 | F9 | Defective cofactor function of FVIIIa variant |
| REAC:R-HSA-9672383 | 0.0499419797295 | 0.5 | F9 | Defective factor IX causes thrombophilia |
| REAC:R-HSA-9673240 | 0.0499419797295 | 0.5 | F9 | Defective gamma-carboxylation of F9 |
| HP:0033061 | 0.0499436884913 | 0.5 | F9 | Increased factor IX activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| F9 | LMLN | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| F9 | huMAP3_00663.1 huMAP3_03151.1 huMAP3_03499.1 huMAP3_05776.1 huMAP3_09814.1 huMAP3_09919.1 huMAP3_11798.1 |
| LMLN | huMAP3_03151.1 huMAP3_06873.1 huMAP3_09919.1 huMAP3_10805.1 |