hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03169.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MYH14 | Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C) | 5 | UniProt NCBI |
| MYL3 | Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb) | 5 | UniProt NCBI |
| MYL6 | Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04814 | 3.63333755269e-05 | 1.0 | MYH14 MYL3 MYL6 | Motor proteins |
| GO:0016460 | 0.000170228592746 | 1.0 | MYH14 MYL3 MYL6 | myosin II complex |
| GO:0016459 | 0.000476755403739 | 1.0 | MYH14 MYL3 MYL6 | myosin complex |
| REAC:R-HSA-5627117 | 0.0011650518872 | 0.666666666667 | MYH14 MYL6 | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5625900 | 0.0011650518872 | 0.666666666667 | MYH14 MYL6 | RHO GTPases activate CIT |
| REAC:R-HSA-416572 | 0.0011650518872 | 0.666666666667 | MYH14 MYL6 | Sema4D induced cell migration and growth-cone collapse |
| REAC:R-HSA-5627123 | 0.00129444299395 | 0.666666666667 | MYH14 MYL6 | RHO GTPases activate PAKs |
| REAC:R-HSA-400685 | 0.00172341693863 | 0.666666666667 | MYH14 MYL6 | Sema4D in semaphorin signaling |
| REAC:R-HSA-3928663 | 0.00221357222266 | 0.666666666667 | MYH14 MYL6 | EPHA-mediated growth cone collapse |
| KEGG:04270 | 0.00346604271076 | 0.666666666667 | MYH14 MYL6 | Vascular smooth muscle contraction |
| KEGG:04530 | 0.00727572841175 | 0.666666666667 | MYH14 MYL6 | Tight junction |
| REAC:R-HSA-373755 | 0.0116360425406 | 0.666666666667 | MYH14 MYL6 | Semaphorin interactions |
| REAC:R-HSA-5625740 | 0.0220121799777 | 0.666666666667 | MYH14 MYL6 | RHO GTPases activate PKNs |
| REAC:R-HSA-2682334 | 0.02256145142 | 0.666666666667 | MYH14 MYL6 | EPH-Ephrin signaling |
| GO:0007517 | 0.0468435252984 | 1.0 | MYH14 MYL3 MYL6 | muscle organ development |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MYH14 | MYL6 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| MYL6 | MYL3 | 0.975 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MYH14 | MYL3 | 0.947 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes