hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03174.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EXOC3L2 | Exocyst complex component 3-like protein 2 (HBV X-transactivated gene 7 protein) (HBV XAg-transactivated protein 7) | 3 | UniProt NCBI |
| SIAH1 | E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) | 5 | UniProt NCBI |
| PRR20C | Proline-rich protein 20C | 5 | UniProt NCBI |
| SIAH2 | E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2) | 5 | UniProt NCBI |
| JSRP1 | Junctional sarcoplasmic reticulum protein 1 (Junctional-face membrane protein of 45 kDa homolog) (JP-45) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2359 | 0.00578263137464 | 0.5 | SIAH1 SIAH2 | Parkin ubiquitin proteasomal system pathway |
| REAC:R-HSA-373752 | 0.0068064250699 | 0.5 | SIAH1 SIAH2 | Netrin-1 signaling |
| WP:WP4751 | 0.0248784837172 | 0.25 | SIAH1 | HIPK2 in kidney fibrosis |
| REAC:R-HSA-977225 | 0.0453901932463 | 0.5 | SIAH1 SIAH2 | Amyloid fiber formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SIAH1 | SIAH2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| JSRP1 | SIAH1 | 0.995 | 0.028 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| EXOC3L2 | SIAH1 | 0.994 | 0.084 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PRR20C | SIAH2 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM | |
| SIAH1 | PRR20C | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM |
Related Complexes