hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03180.1
Complex Portal: CPX-17762
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MARK2 | Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b) | 5 | UniProt NCBI |
| CLASP2 | CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2) | 5 | UniProt NCBI |
| MTCL1 | Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2) | 5 | UniProt NCBI |
| MTCL2 | Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0097427 | 0.0280843539964 | 0.5 | MTCL1 MARK2 | microtubule bundle |
| GO:0099513 | 0.0333098536164 | 1.0 | MTCL2 CLASP2 MARK2 MTCL1 | polymeric cytoskeletal fiber |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MTCL2 | MTCL1 | 0.998 | 0.08 | hein_WMM bioplex_WMM bioplex3_WMM hein () | |
| MARK2 | MTCL2 | 0.987 | 0.048 | hein_WMM bioplex3_WMM boldt hein () boldt_WMM | |
| MARK2 | MTCL1 | 0.985 | 0.044 | hein_WMM bioplex3_WMM hein () | |
| MARK2 | CLASP2 | 0.967 | 0.12 | hein_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM treiber_WMM | |
| CLASP2 | MTCL2 | 0.963 | 0.022 | hein_WMM bioplex3_WMM boldt hein () boldt_WMM | |
| CLASP2 | MTCL1 | 0.695 | 0.054 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes