hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_03193.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
TFAP2A	Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)	5	UniProt NCBI
TFAP2B	Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta)	5	UniProt NCBI
TFAP2D	Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1)	5	UniProt NCBI
TMOD2	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)	5	UniProt NCBI

Showing 1 to 4 of 4 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8866904	1.17833531486e-07	0.75	TFAP2A TFAP2D TFAP2B	Negative regulation of activity of TFAP2 (AP-2) family transcription factors
REAC:R-HSA-8866907	1.68324973574e-07	0.75	TFAP2A TFAP2D TFAP2B	Activation of the TFAP2 (AP-2) family of transcription factors
REAC:R-HSA-8864260	7.64413736449e-06	0.75	TFAP2A TFAP2D TFAP2B	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
HPA:0410552	0.000195847962419	0.5	TFAP2B TFAP2A	retina; ganglion cells [>=Medium]
HPA:0410551	0.000395903520345	0.5	TFAP2B TFAP2A	retina; ganglion cells [>=Low]
WP:WP4352	0.000518672840556	0.75	TFAP2A TFAP2D TFAP2B	Ciliary landscape
HPA:0411232	0.000591517957266	0.5	TFAP2B TFAP2A	retina; inner nuclear layer[>=Medium]
REAC:R-HSA-8866910	0.000676052383047	0.5	TFAP2B TFAP2A	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
HPA:0411231	0.000826159052053	0.5	TFAP2B TFAP2A	retina; inner nuclear layer[>=Low]
WP:WP2064	0.00685264055756	0.5	TFAP2B TFAP2A	Neural crest differentiation

Showing 1 to 10 of 13 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
TFAP2A	TFAP2D	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
TMOD2	TFAP2A	0.989	0.076	bioplex3_WMM bioplex3_HCT116 WMM_only
TFAP2B	TFAP2A	0.988		bioplex3_HEK293 bioplex3_WMM WMM_only
TFAP2B	TFAP2D	0.977		bioplex3_HEK293 bioplex3_WMM WMM_only
TMOD2	TFAP2D	0.958		bioplex3_HEK293 bioplex3_WMM WMM_only

Showing 1 to 5 of 5 entries

Related Complexes

Genename	Complexes
TFAP2D	huMAP3_01365.1 huMAP3_03193.1 huMAP3_08604.1
TFAP2B	huMAP3_01365.1 huMAP3_02506.1 huMAP3_03193.1 huMAP3_06567.1 huMAP3_07334.1 huMAP3_08604.1 huMAP3_12543.1
TFAP2A	huMAP3_01365.1 huMAP3_03193.1 huMAP3_08604.1
TMOD2	huMAP3_01365.1 huMAP3_03193.1