hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03245.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GNPDA2 | Glucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2) (Glucosamine-6-phosphate isomerase SB52) | 5 | UniProt NCBI |
| GNPDA1 | Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin) | 5 | UniProt NCBI |
| AMDHD2 | N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0006046 | 9.61200410764e-08 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | N-acetylglucosamine catabolic process |
| KEGG:00520 | 7.41273577649e-07 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | Amino sugar and nucleotide sugar metabolism |
| GO:0019262 | 3.36420143768e-06 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | N-acetylneuraminate catabolic process |
| GO:0006048 | 5.38272230028e-06 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | UDP-N-acetylglucosamine biosynthetic process |
| GO:1901072 | 8.07408345042e-06 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | glucosamine-containing compound catabolic process |
| GO:0006047 | 8.07408345042e-06 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | UDP-N-acetylglucosamine metabolic process |
| GO:0046349 | 8.07408345042e-06 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | amino sugar biosynthetic process |
| GO:0006054 | 1.58598067776e-05 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | N-acetylneuraminate metabolic process |
| GO:0006044 | 2.74903317479e-05 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | N-acetylglucosamine metabolic process |
| GO:0046348 | 3.49876949518e-05 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | amino sugar catabolic process |
| GO:0009226 | 7.84339535184e-05 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | nucleotide-sugar biosynthetic process |
| GO:1901071 | 0.000109576846827 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | glucosamine-containing compound metabolic process |
| GO:0009225 | 0.000281151120149 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | nucleotide-sugar metabolic process |
| GO:0006040 | 0.000575182325801 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | amino sugar metabolic process |
| GO:0004342 | 0.00140460216025 | 0.666666666667 | GNPDA2 GNPDA1 | glucosamine-6-phosphate deaminase activity |
| GO:0006043 | 0.00140460216025 | 0.666666666667 | GNPDA2 GNPDA1 | glucosamine catabolic process |
| GO:0006041 | 0.00421361424067 | 0.666666666667 | GNPDA2 GNPDA1 | glucosamine metabolic process |
| REAC:R-HSA-70171 | 0.0141416283812 | 0.666666666667 | GNPDA2 GNPDA1 | Glycolysis |
| GO:0016810 | 0.0146194737676 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| KEGG:01100 | 0.0189521995452 | 1.0 | GNPDA2 AMDHD2 GNPDA1 | Metabolic pathways |
| REAC:R-HSA-70326 | 0.0209338694285 | 0.666666666667 | GNPDA2 GNPDA1 | Glucose metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GNPDA1 | AMDHD2 | 1.0 | 0.16 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM Malo bioplex3_HCT116 fraction |
| GNPDA2 | AMDHD2 | 1.0 | 0.13 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM Malo bioplex3_HCT116 fraction |
| GNPDA2 | GNPDA1 | 0.999 | 0.68 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes