hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03247.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADH1A | Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha) | 5 | UniProt NCBI |
| ADH1B | All-trans-retinol dehydrogenase [NAD(+)] ADH1B (EC 1.1.1.105) (Alcohol dehydrogenase 1B) (Alcohol dehydrogenase subunit beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP206 | 3.31996874241e-05 | 1.0 | ADH1A ADH1B | Fatty acid omega oxidation |
| KEGG:00350 | 5.70619627602e-05 | 1.0 | ADH1A ADH1B | Tyrosine metabolism |
| REAC:R-HSA-71384 | 9.39818963671e-05 | 1.0 | ADH1A ADH1B | Ethanol oxidation |
| KEGG:00071 | 0.000126804361689 | 1.0 | ADH1A ADH1B | Fatty acid degradation |
| KEGG:00620 | 0.000146800434109 | 1.0 | ADH1A ADH1B | Pyruvate metabolism |
| WP:WP3996 | 0.000160890792901 | 1.0 | ADH1A ADH1B | Ethanol effects on histone modifications |
| KEGG:00830 | 0.000207276360454 | 1.0 | ADH1A ADH1B | Retinol metabolism |
| KEGG:00982 | 0.000232637232791 | 1.0 | ADH1A ADH1B | Drug metabolism - cytochrome P450 |
| KEGG:00980 | 0.000278156747244 | 1.0 | ADH1A ADH1B | Metabolism of xenobiotics by cytochrome P450 |
| KEGG:00010 | 0.000307419292249 | 1.0 | ADH1A ADH1B | Glycolysis / Gluconeogenesis |
| HPA:0400653 | 0.00106518672821 | 1.0 | ADH1A ADH1B | rectum; fibroblasts[High] |
| KEGG:04936 | 0.00123975649005 | 1.0 | ADH1A ADH1B | Alcoholic liver disease |
| HPA:0130652 | 0.00241021064773 | 1.0 | ADH1A ADH1B | colon; fibroblasts[>=Medium] |
| HPA:0130651 | 0.00291933379579 | 1.0 | ADH1A ADH1B | colon; fibroblasts[>=Low] |
| HPA:0400652 | 0.00309987391922 | 1.0 | ADH1A ADH1B | rectum; fibroblasts[>=Medium] |
| HPA:0400651 | 0.00380819300345 | 1.0 | ADH1A ADH1B | rectum; fibroblasts[>=Low] |
| REAC:R-HSA-211945 | 0.00499983688673 | 1.0 | ADH1A ADH1B | Phase I - Functionalization of compounds |
| GO:0004024 | 0.00702301080125 | 1.0 | ADH1A ADH1B | alcohol dehydrogenase activity, zinc-dependent |
| HPA:0481322 | 0.00794557083195 | 1.0 | ADH1A ADH1B | small intestine; enterocytes - Microvilli[>=Medium] |
| GO:0004022 | 0.00983221512175 | 1.0 | ADH1A ADH1B | alcohol dehydrogenase (NAD+) activity |
| GO:0006069 | 0.00983221512175 | 1.0 | ADH1A ADH1B | ethanol oxidation |
| HPA:0481321 | 0.0106915861093 | 1.0 | ADH1A ADH1B | small intestine; enterocytes - Microvilli[>=Low] |
| GO:0018455 | 0.0131096201623 | 1.0 | ADH1A ADH1B | alcohol dehydrogenase [NAD(P)+] activity |
| HPA:0151352 | 0.0138444184647 | 1.0 | ADH1A ADH1B | duodenum; paneth cells[>=Medium] |
| HPA:0030442 | 0.0158484138347 | 1.0 | ADH1A ADH1B | appendix; non-germinal center cells[>=Medium] |
| HPA:0151351 | 0.0165465023119 | 1.0 | ADH1A ADH1B | duodenum; paneth cells[>=Low] |
| GO:0006067 | 0.0210690324038 | 1.0 | ADH1A ADH1B | ethanol metabolic process |
| REAC:R-HSA-211859 | 0.0225607814134 | 1.0 | ADH1A ADH1B | Biological oxidations |
| HPA:0150892 | 0.0243548626501 | 1.0 | ADH1A ADH1B | duodenum; goblet cells[>=Medium] |
| HPA:0030441 | 0.0253929683598 | 1.0 | ADH1A ADH1B | appendix; non-germinal center cells[>=Low] |
| HPA:0031292 | 0.0293847104887 | 1.0 | ADH1A ADH1B | appendix; endocrine cells[>=Medium] |
| HPA:0031302 | 0.0295730740175 | 1.0 | ADH1A ADH1B | appendix; enterocytes[>=Medium] |
| HPA:0030891 | 0.0305239186675 | 1.0 | ADH1A ADH1B | appendix; goblet cells[>=Low] |
| HPA:0401332 | 0.0336677240168 | 1.0 | ADH1A ADH1B | rectum; mucosal lymphoid cells[>=Medium] |
| HPA:0150891 | 0.0342743388315 | 1.0 | ADH1A ADH1B | duodenum; goblet cells[>=Low] |
| HPA:0480891 | 0.0350915837902 | 1.0 | ADH1A ADH1B | small intestine; goblet cells[>=Low] |
| HPA:0031291 | 0.0367549601274 | 1.0 | ADH1A ADH1B | appendix; endocrine cells[>=Low] |
| HPA:0151302 | 0.0401972584807 | 1.0 | ADH1A ADH1B | duodenum; enterocytes[>=Medium] |
| HPA:0151292 | 0.0440235054965 | 1.0 | ADH1A ADH1B | duodenum; endocrine cells[>=Medium] |
| HPA:0031301 | 0.0485057149607 | 1.0 | ADH1A ADH1B | appendix; enterocytes[>=Low] |
| GO:0004745 | 0.0491610756088 | 1.0 | ADH1A ADH1B | NAD-retinol dehydrogenase activity |
| HPA:0481291 | 0.0499662845592 | 1.0 | ADH1A ADH1B | small intestine; endocrine cells[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ADH1A | ADH1B | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ADH1A | huMAP3_02108.1 huMAP3_03046.1 huMAP3_03247.1 |
| ADH1B | huMAP3_02108.1 huMAP3_03247.1 |