hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03279.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RRM2B | Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2) | 5 | UniProt NCBI |
| RRM2 | Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4584 | 3.31996874241e-05 | 1.0 | RRM2B RRM2 | Biomarkers for pyrimidine metabolism disorders |
| WP:WP4225 | 6.51224637934e-05 | 1.0 | RRM2B RRM2 | Pyrimidine metabolism and related diseases |
| KEGG:00240 | 0.000160943997529 | 1.0 | RRM2B RRM2 | Pyrimidine metabolism |
| KEGG:00480 | 0.00019914787573 | 1.0 | RRM2B RRM2 | Glutathione metabolism |
| KEGG:04115 | 0.000327740504058 | 1.0 | RRM2B RRM2 | p53 signaling pathway |
| KEGG:00983 | 0.000359441594481 | 1.0 | RRM2B RRM2 | Drug metabolism - other enzymes |
| KEGG:01232 | 0.000392605812153 | 1.0 | RRM2B RRM2 | Nucleotide metabolism |
| REAC:R-HSA-499943 | 0.000432316723289 | 1.0 | RRM2B RRM2 | Interconversion of nucleotide di- and triphosphates |
| KEGG:00230 | 0.000772693757832 | 1.0 | RRM2B RRM2 | Purine metabolism |
| GO:0005971 | 0.00140460216025 | 1.0 | RRM2B RRM2 | ribonucleoside-diphosphate reductase complex |
| GO:0061731 | 0.00140460216025 | 1.0 | RRM2B RRM2 | ribonucleoside-diphosphate reductase activity |
| GO:0004748 | 0.00140460216025 | 1.0 | RRM2B RRM2 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| GO:0016728 | 0.00468200720083 | 1.0 | RRM2B RRM2 | oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor |
| REAC:R-HSA-15869 | 0.00499983688673 | 1.0 | RRM2B RRM2 | Metabolism of nucleotides |
| GO:0009265 | 0.0131096201623 | 1.0 | RRM2B RRM2 | 2'-deoxyribonucleotide biosynthetic process |
| GO:0009263 | 0.0131096201623 | 1.0 | RRM2B RRM2 | deoxyribonucleotide biosynthetic process |
| GO:0046385 | 0.0131096201623 | 1.0 | RRM2B RRM2 | deoxyribose phosphate biosynthetic process |
| GO:0016725 | 0.0210690324038 | 1.0 | RRM2B RRM2 | oxidoreductase activity, acting on CH or CH2 groups |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RRM2B | RRM2 | 1.0 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| RRM2B | huMAP3_03279.1 huMAP3_04931.1 huMAP3_07989.1 huMAP3_11033.1 huMAP3_12490.1 huMAP3_13744.1 |
| RRM2 | huMAP3_03279.1 huMAP3_03388.1 huMAP3_07989.1 huMAP3_11033.1 huMAP3_12747.1 |