hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03295.1
Complex Portal: CPX-20710
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ORAI1 | Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A) | 5 | UniProt NCBI |
| PIGX | Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X) | 4 | UniProt NCBI |
| AASS | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:828 | 0.0249718442456 | 0.333333333333 | ORAI1 | TRPC1-STIM1-ORAI1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ORAI1 | AASS | 0.962 | 0.04 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ORAI1 | PIGX | 0.961 | 0.1 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PIGX | AASS | 0.223 | 0.038 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes