hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03303.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CACHD1 | VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) | 4 | UniProt NCBI |
| ST8SIA2 | Alpha-2,8-sialyltransferase 8B (EC 2.4.3.-) (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase St8Sia II) (ST8SiaII) (Sialyltransferase X) (STX) | 5 | UniProt NCBI |
| ST8SIA4 | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV) | 5 | UniProt NCBI |
| RNASEL | 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-419037 | 0.00359044851421 | 0.5 | ST8SIA2 ST8SIA4 | NCAM1 interactions |
| REAC:R-HSA-4085001 | 0.00444848198459 | 0.5 | ST8SIA2 ST8SIA4 | Sialic acid metabolism |
| REAC:R-HSA-375165 | 0.008795277704 | 0.5 | ST8SIA2 ST8SIA4 | NCAM signaling for neurite out-growth |
| REAC:R-HSA-446219 | 0.0168610262513 | 0.5 | ST8SIA2 ST8SIA4 | Synthesis of substrates in N-glycan biosythesis |
| REAC:R-HSA-446193 | 0.0267695204965 | 0.5 | ST8SIA2 ST8SIA4 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| GO:0003828 | 0.042122686785 | 0.5 | ST8SIA2 ST8SIA4 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ST8SIA2 | ST8SIA4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RNASEL | ST8SIA4 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CACHD1 | ST8SIA4 | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RNASEL | CACHD1 | 0.106 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes