hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03320.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CRB3 | Protein crumbs homolog 3 | 5 | UniProt NCBI |
| PALS1 | Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9705677 | 1.70876175213e-05 | 1.0 | PALS1 CRB3 | SARS-CoV-2 targets PDZ proteins in cell-cell junction |
| REAC:R-HSA-420029 | 0.000179419983974 | 1.0 | PALS1 CRB3 | Tight junction interactions |
| KEGG:04530 | 0.00155920593969 | 1.0 | PALS1 CRB3 | Tight junction |
| REAC:R-HSA-421270 | 0.00169167413461 | 1.0 | PALS1 CRB3 | Cell-cell junction organization |
| WP:WP4239 | 0.00368005765986 | 1.0 | PALS1 CRB3 | Epithelial to mesenchymal transition in colorectal cancer |
| REAC:R-HSA-446728 | 0.00436759503844 | 1.0 | PALS1 CRB3 | Cell junction organization |
| KEGG:05165 | 0.00700203931066 | 1.0 | PALS1 CRB3 | Human papillomavirus infection |
| REAC:R-HSA-1500931 | 0.00897612548393 | 1.0 | PALS1 CRB3 | Cell-Cell communication |
| REAC:R-HSA-9692912 | 0.0249718442457 | 0.5 | PALS1 | SARS-CoV-1 targets PDZ proteins in cell-cell junction |
| HPA:0410563 | 0.0263823282362 | 0.5 | PALS1 | retina; limiting membrane[High] |
| REAC:R-HSA-9705683 | 0.0300366140789 | 1.0 | PALS1 CRB3 | SARS-CoV-2-host interactions |
| CORUM:461 | 0.0499419797295 | 0.5 | PALS1 | MPP4-MPP5-CRB1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CRB3 | PALS1 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes