hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03349.1
Complex Portal: CPX-14323
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FTH1 | Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed] | 5 | UniProt NCBI |
| NCOA4 | Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04216 | 0.000102418907518 | 1.0 | FTH1 NCOA4 | Ferroptosis |
| WP:WP4313 | 0.00070357799118 | 1.0 | FTH1 NCOA4 | Ferroptosis |
| GO:0044754 | 0.0131096201623 | 1.0 | FTH1 NCOA4 | autolysosome |
| GO:0005767 | 0.0257510396046 | 1.0 | FTH1 NCOA4 | secondary lysosome |
| CORUM:6135 | 0.0499419797295 | 0.5 | FTH1 | Ferritin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FTH1 | NCOA4 | 0.999 | 0.184 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes