hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03351.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PMM2 | Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8) | 5 | UniProt   NCBI |
PMM1 | Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8) (PMMH-22) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-446205 | 1.70876175213e-05 | 1.0 | PMM2 PMM1 | Synthesis of GDP-mannose |
  KEGG:00051 | 9.12015985996e-05 | 1.0 | PMM2 PMM1 | Fructose and mannose metabolism |
  KEGG:01250 | 9.67289682117e-05 | 1.0 | PMM2 PMM1 | Biosynthesis of nucleotide sugars |
  KEGG:00520 | 0.000160943997529 | 1.0 | PMM2 PMM1 | Amino sugar and nucleotide sugar metabolism |
  GO:0004615 | 0.000468200720083 | 1.0 | PMM2 PMM1 | phosphomannomutase activity |
  GO:0006013 | 0.00140460216025 | 1.0 | PMM2 PMM1 | mannose metabolic process |
  KEGG:01240 | 0.00144865854745 | 1.0 | PMM2 PMM1 | Biosynthesis of cofactors |
  GO:0009298 | 0.0028092043205 | 1.0 | PMM2 PMM1 | GDP-mannose biosynthetic process |
  REAC:R-HSA-446219 | 0.00282458317627 | 1.0 | PMM2 PMM1 | Synthesis of substrates in N-glycan biosythesis |
  REAC:R-HSA-446193 | 0.00449062588459 | 1.0 | PMM2 PMM1 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
  GO:0019673 | 0.00702301080125 | 1.0 | PMM2 PMM1 | GDP-mannose metabolic process |
  GO:0016868 | 0.016855225923 | 1.0 | PMM2 PMM1 | intramolecular phosphotransferase activity |
  REAC:R-HSA-4043911 | 0.0249718442457 | 0.5 | PMM2 | Defective PMM2 causes PMM2-CDG |
  HP:0012509 | 0.0499436884913 | 0.5 | PMM2 | Reduced thyroxin-binding globulin |
  HP:0012882 | 0.0499436884913 | 0.5 | PMM2 | Hyperplastic labia majora |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 PMM2 |  PMM1 | 1.0 | 0.126           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
Related Complexes
Genename | Complexes |
---|---|
PMM2 | huMAP3_03351.1 huMAP3_10483.1 huMAP3_14332.1 |
PMM1 | huMAP3_03351.1 huMAP3_10483.1 huMAP3_14332.1 |