hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03377.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCO2 | Protein SCO2 homolog, mitochondrial | 5 | UniProt NCBI |
| NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | 5 | UniProt NCBI |
| IRAK1 | Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1) | 5 | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | 5 | UniProt NCBI |
| GGT7 | Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1944 | 0.049938562206 | 0.25 | IRAK1 | IRAK1-IRAK2 complex |
| CORUM:1945 | 0.049938562206 | 0.25 | IRAK1 | IRAK1-IRAK3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NUBP2 | IRAK1 | 0.988 | 0.128 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only |
| GART | IRAK1 | 0.979 | 0.136 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
| GART | NUBP2 | 0.97 | 0.11 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only |
| NUBP2 | GGT7 | 0.962 | 0.07 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only |
| IRAK1 | GGT7 | 0.96 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SCO2 | NUBP2 | 0.955 | 0.0500909090909 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| SCO2 | GGT7 | 0.12 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| SCO2 | IRAK1 | 0.085 | 0.1 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| GART | SCO2 | 0.046 | 0.156 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
| GART | GGT7 | 0.041 | 0.0865588235294 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
Related Complexes