hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_03388.1

Complex Portal: CPX-23522

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
RRM2	Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit)	5	UniProt NCBI
GNPTAB	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	5	UniProt NCBI
BUB1B	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)	5	UniProt NCBI
ANAPC16	Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16)	5	UniProt NCBI
FZR1	Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)	5	UniProt NCBI
CDC20	Cell division cycle protein 20 homolog (p55CDC)	5	UniProt NCBI
ANAPC15	Anaphase-promoting complex subunit 15 (APC15)	5	UniProt NCBI
CDC23	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)	5	UniProt NCBI
ANAPC13	Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)	4	UniProt NCBI
CDC16	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)	5	UniProt NCBI
NEK2	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)	5	UniProt NCBI
ANAPC10	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)	5	UniProt NCBI
CDC26	Anaphase-promoting complex subunit CDC26 (Anaphase-promoting complex subunit 12) (APC12) (Cell division cycle protein 26 homolog)	5	UniProt NCBI
ANAPC7	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)	5	UniProt NCBI
ANAPC4	Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)	5	UniProt NCBI
ANAPC1	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	5	UniProt NCBI
CDC27	Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)	5	UniProt NCBI
ANAPC5	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)	5	UniProt NCBI
CFAP97	Cilia- and flagella-associated protein 97	3	UniProt NCBI
ANAPC2	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)	5	UniProt NCBI
FBXO5	F-box only protein 5 (Early mitotic inhibitor 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005680	1.86520762804e-37	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	anaphase-promoting complex
REAC:R-HSA-179409	2.31050107979e-34	0.7	NEK2 ANAPC10 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	APC-Cdc20 mediated degradation of Nek2A
GO:0031145	2.67170337518e-33	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	anaphase-promoting complex-dependent catabolic process
REAC:R-HSA-176407	2.93828193062e-33	0.65	ANAPC7 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC10 CDC20 CDC23 FZR1	Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
REAC:R-HSA-141430	8.39135281922e-33	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Inactivation of APC/C via direct inhibition of the APC/C complex
REAC:R-HSA-141405	8.39135281922e-33	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
GO:0051445	8.59176980664e-32	0.75	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	regulation of meiotic cell cycle
REAC:R-HSA-174143	6.95444367444e-31	0.8	CDC16 ANAPC10 ANAPC1 CDC23 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	APC/C-mediated degradation of cell cycle proteins
REAC:R-HSA-453276	6.95444367444e-31	0.8	CDC16 ANAPC10 ANAPC1 CDC23 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	Regulation of mitotic cell cycle
GO:0000152	7.84450089498e-31	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	nuclear ubiquitin ligase complex
REAC:R-HSA-9687136	9.95206611818e-30	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Aberrant regulation of mitotic exit in cancer due to RB1 defects
REAC:R-HSA-176408	1.12980761344e-28	0.75	CDC16 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	Regulation of APC/C activators between G1/S and early anaphase
REAC:R-HSA-174048	2.66507065283e-28	0.6	ANAPC7 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC10 CDC20 CDC23	APC/C:Cdc20 mediated degradation of Cyclin B
KEGG:04110	2.0903501628e-27	0.8	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	Cell cycle
REAC:R-HSA-179419	1.52122573295e-26	0.7	NEK2 ANAPC10 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
REAC:R-HSA-176409	2.31958643285e-26	0.7	NEK2 ANAPC10 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	APC/C:Cdc20 mediated degradation of mitotic proteins
REAC:R-HSA-176412	2.4199598212e-26	0.55	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23	Phosphorylation of the APC/C
REAC:R-HSA-176814	2.85085259185e-26	0.7	NEK2 ANAPC10 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
REAC:R-HSA-9687139	1.63481834586e-25	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Aberrant regulation of mitotic cell cycle due to RB1 defects
GO:2000241	3.12065900263e-25	0.75	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	regulation of reproductive process
REAC:R-HSA-9675126	3.62562181626e-25	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Diseases of mitotic cell cycle
REAC:R-HSA-8853884	3.62562181626e-25	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Transcriptional Regulation by VENTX
KEGG:04114	7.7092648294e-25	0.7	ANAPC13 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23	Oocyte meiosis
REAC:R-HSA-174184	6.14820713516e-24	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Cdc20:Phospho-APC/C mediated degradation of Cyclin A
REAC:R-HSA-174178	7.49954498959e-24	0.65	ANAPC7 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC10 CDC20 CDC23 FZR1	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
KEGG:04914	9.05691652978e-24	0.65	ANAPC13 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC2 ANAPC10 CDC26 CDC23 FZR1	Progesterone-mediated oocyte maturation
KEGG:04120	3.65261310175e-23	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	Ubiquitin mediated proteolysis
CORUM:96	8.92233886548e-23	0.4	ANAPC7 CDC23 ANAPC2 ANAPC1 ANAPC5 ANAPC10 CDC16 ANAPC4	Anaphase-promoting complex
GO:0007346	2.75664023348e-22	0.9	ANAPC13 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC16 CDC20 CDC23	regulation of mitotic cell cycle
REAC:R-HSA-174084	5.15416876827e-22	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Autodegradation of Cdh1 by Cdh1:APC/C
REAC:R-HSA-174154	9.4942753243e-22	0.6	ANAPC7 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC10 CDC20 CDC23	APC/C:Cdc20 mediated degradation of Securin
GO:0051321	9.90500925523e-22	0.75	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	meiotic cell cycle
GO:0070979	1.10134147575e-21	0.55	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 ANAPC5 ANAPC2 ANAPC10 CDC26 CDC23 FZR1	protein K11-linked ubiquitination
REAC:R-HSA-69618	2.14322364015e-21	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Mitotic Spindle Checkpoint
REAC:R-HSA-69017	2.4628804265e-21	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	CDK-mediated phosphorylation and removal of Cdc6
GO:0031461	3.46241098191e-21	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	cullin-RING ubiquitin ligase complex
KEGG:05166	9.5361517527e-21	0.7	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC16	Human T-cell leukemia virus 1 infection
REAC:R-HSA-69052	5.21840288723e-20	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Switching of origins to a post-replicative state
REAC:R-HSA-69278	7.09842854547e-20	0.85	CDC16 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC20 CDC23	Cell Cycle, Mitotic
CORUM:93	1.00259635498e-19	0.35	ANAPC7 CDC23 ANAPC2 ANAPC1 ANAPC5 ANAPC4 CDC16	Anaphase-promoting complex
REAC:R-HSA-2559582	1.35333914035e-19	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Senescence-Associated Secretory Phenotype (SASP)
REAC:R-HSA-2555396	2.91217934115e-19	0.7	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 BUB1B CDC20 CDC23	Mitotic Metaphase and Anaphase
REAC:R-HSA-69239	1.78132880723e-18	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Synthesis of DNA
REAC:R-HSA-1640170	2.45808216517e-18	0.85	CDC16 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC20 CDC23	Cell Cycle
REAC:R-HSA-2467813	2.90043910375e-18	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Separation of Sister Chromatids
REAC:R-HSA-68867	5.38022934441e-18	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Assembly of the pre-replicative complex
REAC:R-HSA-68886	7.2038309287e-18	0.75	NEK2 ANAPC10 ANAPC1 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	M Phase
GO:0000151	7.53840549039e-18	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	ubiquitin ligase complex
GO:0000278	2.22355518893e-17	0.9	ANAPC13 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC16 CDC20 CDC23	mitotic cell cycle
REAC:R-HSA-69002	2.48047963211e-17	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	DNA Replication Pre-Initiation
REAC:R-HSA-68882	3.74764076077e-17	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Mitotic Anaphase
REAC:R-HSA-69242	6.55139011884e-17	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	S Phase
WP:WP179	9.46964529991e-17	0.55	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	Cell cycle
GO:0019953	1.01097144161e-16	0.8	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CFAP97 CDC23	sexual reproduction
REAC:R-HSA-69306	1.99126934038e-16	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	DNA Replication
GO:0051726	2.07647566591e-16	0.9	ANAPC13 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC16 CDC20 CDC23	regulation of cell cycle
REAC:R-HSA-2559583	2.13677404815e-16	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Cellular Senescence
REAC:R-HSA-69620	7.23128733135e-16	0.65	ANAPC7 ANAPC10 ANAPC1 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 BUB1B CDC20 CDC23	Cell Cycle Checkpoints
GO:0022414	1.05664552779e-14	0.8	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CFAP97 CDC23	reproductive process
GO:0000003	1.17592093774e-14	0.8	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CFAP97 CDC23	reproduction
GO:0043161	1.32768831935e-14	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	proteasome-mediated ubiquitin-dependent protein catabolic process
REAC:R-HSA-983168	7.19319931636e-14	0.6	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	Antigen processing: Ubiquitination & Proteasome degradation
GO:0007091	2.5538660475e-13	0.5	ANAPC7 CDC16 ANAPC2 ANAPC15 FBXO5 ANAPC1 ANAPC5 BUB1B CDC20 CDC23	metaphase/anaphase transition of mitotic cell cycle
GO:0044784	3.25140819884e-13	0.5	ANAPC7 CDC16 ANAPC2 ANAPC15 FBXO5 ANAPC1 ANAPC5 BUB1B CDC20 CDC23	metaphase/anaphase transition of cell cycle
GO:0010498	3.8741636786e-13	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	proteasomal protein catabolic process
GO:0007049	4.69687686711e-13	0.9	ANAPC13 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC16 CDC20 CDC23	cell cycle
GO:0033045	7.24725662443e-13	0.5	ANAPC7 CDC16 ANAPC2 ANAPC15 FBXO5 ANAPC1 ANAPC5 BUB1B CDC20 CDC23	regulation of sister chromatid segregation
REAC:R-HSA-983169	8.46844641956e-13	0.6	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	Class I MHC mediated antigen processing & presentation
GO:0006511	3.13403915641e-12	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	ubiquitin-dependent protein catabolic process
GO:0019941	3.92926685226e-12	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	modification-dependent protein catabolic process
GO:0043632	5.33009868309e-12	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	modification-dependent macromolecule catabolic process
GO:0016567	6.44888534664e-12	0.7	ANAPC13 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	protein ubiquitination
GO:0051983	7.51689778788e-12	0.5	ANAPC7 CDC16 ANAPC2 ANAPC15 FBXO5 ANAPC1 ANAPC5 BUB1B CDC20 CDC23	regulation of chromosome segregation
GO:0032446	3.88189686545e-11	0.7	ANAPC13 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	protein modification by small protein conjugation
GO:1990234	4.06354275303e-11	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	transferase complex
GO:0000209	4.48046425616e-11	0.55	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 ANAPC5 ANAPC2 ANAPC10 CDC26 CDC23 FZR1	protein polyubiquitination
GO:0051603	5.64053588963e-11	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	proteolysis involved in protein catabolic process
GO:0010965	8.90743665161e-11	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	regulation of mitotic sister chromatid separation
GO:0033044	8.98267572601e-11	0.55	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	regulation of chromosome organization
GO:0140535	9.55340383069e-11	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	intracellular protein-containing complex
GO:0044772	1.02921030144e-10	0.6	CDC16 CDC23 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	mitotic cell cycle phase transition
GO:0007088	1.1129372073e-10	0.45	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 CDC23	regulation of mitotic nuclear division
GO:0051306	1.22974772768e-10	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	mitotic sister chromatid separation
GO:0098813	1.50574415833e-10	0.55	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	nuclear chromosome segregation
GO:0070647	1.53121925995e-10	0.7	ANAPC13 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	protein modification by small protein conjugation or removal
GO:0051783	2.15912789914e-10	0.45	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 CDC23	regulation of nuclear division
GO:0043687	3.8032277302e-10	0.7	ANAPC13 CDC16 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	post-translational protein modification
GO:1905818	6.72903694571e-10	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	regulation of chromosome separation
GO:0010564	8.62641279285e-10	0.65	CDC16 CDC23 NEK2 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	regulation of cell cycle process
GO:0051304	1.3961101895e-09	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	chromosome separation
GO:0044770	1.42991630967e-09	0.6	CDC16 CDC23 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	cell cycle phase transition
GO:0030163	1.49288647122e-09	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	protein catabolic process
GO:0000819	1.50749924068e-09	0.5	ANAPC7 CDC16 ANAPC2 ANAPC15 FBXO5 ANAPC1 ANAPC5 BUB1B CDC20 CDC23	sister chromatid segregation
REAC:R-HSA-1280218	1.96454043304e-09	0.6	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	Adaptive Immune System
GO:1903047	2.36147421438e-09	0.65	CDC16 CDC23 NEK2 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	mitotic cell cycle process
GO:0007059	3.64925924414e-09	0.55	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	chromosome segregation
GO:0030071	4.1269845781e-09	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	regulation of mitotic metaphase/anaphase transition
GO:1902099	5.04055511564e-09	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	regulation of metaphase/anaphase transition of cell cycle
REAC:R-HSA-2262752	5.33272012943e-09	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Cellular responses to stress
REAC:R-HSA-8953897	5.96953804965e-09	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Cellular responses to stimuli
GO:0140513	7.54794878689e-09	0.75	ANAPC13 ANAPC10 ANAPC1 CDC23 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B CDC16 CDC20 FZR1	nuclear protein-containing complex
REAC:R-HSA-212436	1.3985552436e-08	0.65	ANAPC7 CDC16 ANAPC2 RRM2 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 ANAPC16 CDC26 CDC23 FZR1	Generic Transcription Pathway
GO:1901990	2.27918542378e-08	0.5	CDC16 CDC23 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 FZR1	regulation of mitotic cell cycle phase transition
GO:1902494	3.05297361037e-08	0.8	ANAPC13 ANAPC10 ANAPC1 FZR1 ANAPC7 RRM2 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC16 CDC20 CDC23	catalytic complex
REAC:R-HSA-73857	5.55443921635e-08	0.65	ANAPC7 CDC16 ANAPC2 RRM2 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 ANAPC16 CDC26 CDC23 FZR1	RNA Polymerase II Transcription
GO:1901992	1.02159414485e-07	0.35	ANAPC7 CDC16 FBXO5 RRM2 ANAPC5 CDC20 CDC23	positive regulation of mitotic cell cycle phase transition
GO:0009057	1.14195239604e-07	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	macromolecule catabolic process
GO:0006508	1.23444843152e-07	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	proteolysis
GO:1901565	1.26678665957e-07	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	organonitrogen compound catabolic process
REAC:R-HSA-74160	2.66001588842e-07	0.65	ANAPC7 CDC16 ANAPC2 RRM2 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 ANAPC16 CDC26 CDC23 FZR1	Gene expression (Transcription)
GO:0045842	2.77342308517e-07	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of mitotic metaphase/anaphase transition
GO:1902101	2.77342308517e-07	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of metaphase/anaphase transition of cell cycle
GO:0140014	3.12381230788e-07	0.45	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 CDC23	mitotic nuclear division
GO:1901987	3.14951921297e-07	0.5	CDC16 CDC23 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 FZR1	regulation of cell cycle phase transition
GO:0051276	4.47271104095e-07	0.55	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	chromosome organization
GO:1901989	5.37448932388e-07	0.35	ANAPC7 CDC16 FBXO5 RRM2 ANAPC5 CDC20 CDC23	positive regulation of cell cycle phase transition
GO:0045931	9.61859606772e-07	0.35	ANAPC7 CDC16 FBXO5 RRM2 ANAPC5 CDC20 CDC23	positive regulation of mitotic cell cycle
GO:0000070	1.025229093e-06	0.4	ANAPC7 CDC16 FBXO5 ANAPC15 ANAPC5 BUB1B CDC20 CDC23	mitotic sister chromatid segregation
GO:1901970	1.18288915211e-06	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of mitotic sister chromatid separation
GO:0022402	1.27870011081e-06	0.65	CDC16 CDC23 NEK2 ANAPC7 RRM2 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 FZR1	cell cycle process
GO:0000280	6.10788073992e-06	0.45	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 CDC23	nuclear division
GO:1905820	1.34527228796e-05	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of chromosome separation
REAC:R-HSA-176417	1.35764294999e-05	0.15	FBXO5 FZR1 CDC20	Phosphorylation of Emi1
GO:1901575	1.47809042306e-05	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	organic substance catabolic process
GO:0048285	1.72184442815e-05	0.45	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC5 BUB1B CDC20 CDC23	organelle fission
REAC:R-HSA-1643685	2.08589176439e-05	0.6	ANAPC7 CDC16 ANAPC2 ANAPC16 ANAPC4 ANAPC15 ANAPC1 ANAPC5 ANAPC10 CDC26 CDC23 FZR1	Disease
GO:0045840	2.7470374868e-05	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of mitotic nuclear division
GO:0051785	5.92079814967e-05	0.25	ANAPC7 CDC16 ANAPC5 CDC20 CDC23	positive regulation of nuclear division
CORUM:5361	6.49329465809e-05	0.1	ANAPC7 CDC16	Cell division cycle complex (CDC27, CDC16, ANAPC7)
GO:0036211	6.54764794815e-05	0.75	ANAPC13 CDC16 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	protein modification process
REAC:R-HSA-168256	8.65491612925e-05	0.6	ANAPC13 CDC16 ANAPC7 ANAPC4 ANAPC1 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	Immune System
GO:0090068	0.000162769449167	0.35	ANAPC7 CDC16 FBXO5 RRM2 ANAPC5 CDC20 CDC23	positive regulation of cell cycle process
GO:0043412	0.000211369168771	0.75	ANAPC13 CDC16 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC1 FBXO5 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC20 CDC23 FZR1	macromolecule modification
GO:0033043	0.000223244473066	0.55	NEK2 CDC16 ANAPC7 ANAPC15 FBXO5 ANAPC1 ANAPC5 ANAPC2 BUB1B CDC20 CDC23	regulation of organelle organization
GO:0009056	0.000280600752506	0.7	ANAPC13 ANAPC1 FZR1 ANAPC7 ANAPC16 ANAPC4 ANAPC15 CDC26 ANAPC5 ANAPC2 ANAPC10 CDC16 CDC20 CDC23	catabolic process
CORUM:190	0.00038895809385	0.1	BUB1B CDC20	Mitotic checkpoint complex (MCC)
GO:0019538	0.000558463734655	0.85	ANAPC13 ANAPC1 CDC23 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 GNPTAB CDC26 ANAPC2 ANAPC10 ANAPC5 CDC16 CDC20 FZR1	protein metabolic process
GO:0045787	0.00103870458033	0.35	ANAPC7 CDC16 FBXO5 RRM2 ANAPC5 CDC20 CDC23	positive regulation of cell cycle
HPA:0310431	0.00159473781794	0.8	NEK2 ANAPC1 CDC23 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 GNPTAB CDC26 ANAPC2 ANAPC10 ANAPC16 ANAPC5 CDC20 CDC16	lymph node; germinal center cells[>=Low]
GO:0010997	0.00915637133828	0.15	FBXO5 FZR1 CDC20	anaphase-promoting complex binding
GO:0033046	0.0138017804915	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of sister chromatid segregation
GO:0045841	0.0138017804915	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of mitotic metaphase/anaphase transition
GO:0033048	0.0138017804915	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of mitotic sister chromatid segregation
GO:2000816	0.0138017804915	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of mitotic sister chromatid separation
GO:1901564	0.0140266706393	0.85	ANAPC13 ANAPC1 CDC23 NEK2 ANAPC7 ANAPC16 ANAPC4 ANAPC15 FBXO5 GNPTAB CDC26 ANAPC2 ANAPC10 ANAPC5 CDC16 CDC20 FZR1	organonitrogen compound metabolic process
REAC:R-HSA-174113	0.0161466146549	0.15	FBXO5 FZR1 CDC20	SCF-beta-TrCP mediated degradation of Emi1
GO:1905819	0.0167097438311	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of chromosome separation
GO:1902100	0.0167097438311	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of metaphase/anaphase transition of cell cycle
GO:0051985	0.0167097438311	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of chromosome segregation
WP:WP4240	0.0197920993247	0.1	BUB1B CDC20	Regulation of sister chromatid separation at the metaphase anaphase transition
GO:0033047	0.0238671820955	0.2	ANAPC15 FBXO5 BUB1B CDC20	regulation of mitotic sister chromatid segregation
GO:0045839	0.025965921633	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of mitotic nuclear division
GO:0010948	0.0273495495134	0.3	NEK2 FZR1 ANAPC15 FBXO5 BUB1B CDC20	negative regulation of cell cycle process
GO:0051784	0.0330908087031	0.2	ANAPC15 FBXO5 BUB1B CDC20	negative regulation of nuclear division
GO:0005829	0.0370667451336	0.85	CDC16 ANAPC10 ANAPC1 FZR1 NEK2 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 CDC26 ANAPC5 ANAPC2 BUB1B ANAPC16 CDC20 CDC23	cytosol
HPA:0310000	0.0455931704824	0.8	NEK2 ANAPC1 CDC23 ANAPC7 RRM2 ANAPC4 ANAPC15 FBXO5 GNPTAB CDC26 ANAPC2 ANAPC10 ANAPC16 ANAPC5 CDC20 CDC16	lymph node
CORUM:1932	0.0499436884912	0.05	NEK2	NEK2-NEK11 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ANAPC4	ANAPC5	1.0	0.468	structurally_consistent (dimer)
ANAPC1	ANAPC5	1.0	0.79	structurally_consistent (dimer)
CDC16	ANAPC1	1.0	0.498
CDC16	ANAPC4	1.0	0.276
ANAPC16	ANAPC4	1.0	0.15
CDC23	CDC16	1.0	0.752
ANAPC5	ANAPC2	1.0	0.436
ANAPC16	ANAPC1	1.0	0.194
CDC16	ANAPC5	1.0	0.408
ANAPC4	ANAPC2	1.0	0.418	structurally_consistent (dimer)
ANAPC16	CDC23	1.0	0.244
ANAPC16	ANAPC7	1.0	0.534
CDC16	ANAPC2	1.0	0.348
CDC26	ANAPC1	1.0	0.218
ANAPC16	CDC27	1.0	0.296	structurally_consistent (dimer)
ANAPC16	ANAPC2	1.0	0.29
CDC26	ANAPC4	1.0	0.062
CDC26	ANAPC2	1.0	0.194
ANAPC16	ANAPC5	1.0	0.336
CDC16	CDC27	1.0	0.124	structurally_consistent (dimer)
CDC16	ANAPC10	1.0	0.21	structurally_consistent (P30260) structurally_consistent (dimer)
CDC23	ANAPC4	1.0	0.586	structurally_consistent (Q9UJX4)
ANAPC10	ANAPC4	1.0	0.232
CDC23	CDC27	1.0	0.188
CDC26	ANAPC7	1.0	0.106
ANAPC13	ANAPC2	1.0	0.088
CDC23	ANAPC5	1.0	0.628	structurally_consistent (dimer)
CDC26	ANAPC5	1.0	0.15
ANAPC7	ANAPC5	1.0	0.436
ANAPC16	CDC16	1.0	0.18	structurally_consistent (P30260)
ANAPC4	CDC27	1.0	0.186	structurally_consistent (Q9UJX6)
FZR1	CDC16	1.0	0.132
ANAPC4	ANAPC1	1.0	0.402	structurally_consistent (Q9UJX6)
ANAPC1	CDC27	1.0	0.354	structurally_consistent (Q9UJX6)
ANAPC13	CDC26	1.0	0.132
ANAPC13	CDC16	1.0	0.086
CDC23	ANAPC10	1.0	0.262	structurally_consistent (dimer)
ANAPC10	ANAPC2	1.0	0.236	structurally_consistent (Q9H1A4)
ANAPC16	CDC26	1.0	0.198
ANAPC13	CDC27	1.0	0.122
ANAPC13	ANAPC4	1.0	0.19
CDC23	ANAPC2	1.0	0.226
ANAPC16	ANAPC13	1.0	0.168
CDC27	ANAPC2	1.0	0.088	structurally_consistent (dimer)
ANAPC7	ANAPC2	1.0	0.19
ANAPC1	ANAPC2	1.0	0.448	structurally_consistent (dimer)
CDC26	CDC27	1.0	0.166	structurally_consistent (Q9UM11)
ANAPC10	ANAPC5	1.0	0.208	structurally_consistent (Q9H1A4)
CDC16	CDC26	1.0	0.186
ANAPC16	ANAPC10	1.0	0.354
FZR1	CDC26	1.0	0.1	structurally_consistent (dimer)
ANAPC10	CDC26	1.0	0.208	mutually_exclusive (O43684)
ANAPC13	ANAPC10	1.0	0.176
ANAPC7	ANAPC4	1.0	0.3
FZR1	CDC23	1.0	0.138
CDC23	CDC26	1.0	0.112
CDC27	ANAPC5	1.0	0.486
ANAPC13	ANAPC1	1.0	0.17
ANAPC13	ANAPC7	1.0	0.136
ANAPC10	CDC27	1.0	0.172	structurally_consistent (Q9UM11) structurally_consistent (dimer)
ANAPC7	ANAPC1	1.0	0.416
ANAPC13	ANAPC5	1.0	0.132
CDC23	ANAPC13	1.0	0.166
CDC26	FBXO5	1.0	0.156
FZR1	CDC27	1.0	0.08	structurally_consistent (dimer)
FZR1	ANAPC2	1.0	0.07
ANAPC2	FBXO5	0.999	0.052
FZR1	ANAPC16	0.999	0.128	structurally_consistent (dimer)
ANAPC7	FBXO5	0.999	0.212
ANAPC10	FBXO5	0.999	0.15
CDC23	ANAPC1	0.999	0.528	structurally_consistent (Q9UM13)
ANAPC10	ANAPC7	0.999	0.274
FZR1	ANAPC5	0.999	0.08
CDC16	FBXO5	0.999	0.132
ANAPC16	FBXO5	0.999	0.082
CDC23	FBXO5	0.999	0.174
FZR1	ANAPC4	0.999	0.134
CDC27	FBXO5	0.999	0.174
CDC23	ANAPC7	0.999	0.548
ANAPC7	CDC27	0.999	0.622
CDC16	ANAPC7	0.999	0.188
FZR1	ANAPC1	0.999	0.19
ANAPC10	ANAPC1	0.999	0.282	structurally_consistent (dimer)
NEK2	ANAPC2	0.999	0.16
FZR1	ANAPC7	0.999	0.124
ANAPC5	FBXO5	0.999	0.114
FZR1	FBXO5	0.999	0.12
ANAPC1	FBXO5	0.999	0.121333333333
FZR1	ANAPC10	0.999	0.16	mutually_exclusive (O43684) structurally_consistent (dimer)
CDC20	CDC26	0.999	0.228206185567
FZR1	RRM2	0.998	0.092	structurally_consistent (dimer)
BUB1B	ANAPC2	0.998	0.116
CDC20	ANAPC5	0.998	0.098
FZR1	ANAPC13	0.998	0.076
CDC20	FBXO5	0.998	0.15637037037
ANAPC4	FBXO5	0.998	0.168
BUB1B	CDC20	0.998	0.212	structurally_consistent (dimer)
RRM2	ANAPC2	0.997	0.042
CDC20	ANAPC2	0.997	0.108
CDC20	CDC16	0.997	0.068	structurally_consistent (Q9UM13)
ANAPC16	NEK2	0.997	0.222
GNPTAB	ANAPC2	0.996	0.192
CDC20	ANAPC13	0.996	0.162
ANAPC13	FBXO5	0.996	0.102
RRM2	CDC26	0.996	0.088
ANAPC16	CDC20	0.995	0.246
RRM2	FBXO5	0.994	0.178
BUB1B	CDC26	0.994	0.158	mutually_exclusive (O43684)
ANAPC16	CFAP97	0.994	0.122
CDC20	CDC23	0.994	0.0904666666667	structurally_consistent (Q9UM13) structurally_consistent (dimer)
GNPTAB	ANAPC13	0.993	0.084
CFAP97	ANAPC2	0.993	0.148
NEK2	ANAPC5	0.993	0.128
GNPTAB	CDC26	0.993	0.086
ANAPC15	ANAPC5	0.993	0.378
ANAPC15	ANAPC2	0.993	0.29
CDC26	CFAP97	0.992	0.11
CDC20	ANAPC1	0.992	0.206339622642	structurally_consistent (Q9UM13)
NEK2	CDC26	0.992	0.17
GNPTAB	ANAPC16	0.991	0.178
NEK2	ANAPC7	0.991	0.174
RRM2	CDC27	0.991	0.182
CDC27	CFAP97	0.991	0.054
GNPTAB	CDC23	0.991	0.11
ANAPC1	CFAP97	0.99	0.14
CDC23	CFAP97	0.988	0.062
ANAPC16	ANAPC15	0.988	0.144222222222
BUB1B	CDC23	0.988	0.114219858156	structurally_consistent (Q12834)
ANAPC15	CDC23	0.988	0.248
ANAPC15	CDC16	0.988	0.398
RRM2	CDC16	0.987	0.062
ANAPC15	ANAPC4	0.987	0.574
ANAPC15	CDC27	0.987	0.232
GNPTAB	ANAPC7	0.986	0.074
ANAPC15	ANAPC7	0.986	0.252115384615
FZR1	NEK2	0.986	0.192
ANAPC13	CFAP97	0.985	0.068
FZR1	CDC20	0.985	0.138560283688
CDC16	CFAP97	0.985	0.064
GNPTAB	CDC16	0.984	0.068
GNPTAB	ANAPC5	0.984	0.11
RRM2	CDC23	0.984	0.026
RRM2	ANAPC16	0.984	0.108	mutually_exclusive (Q9UM11)
ANAPC15	ANAPC1	0.982	0.464
CFAP97	FBXO5	0.982	0.182
FZR1	CFAP97	0.981	0.114
ANAPC13	NEK2	0.981	0.178
GNPTAB	FBXO5	0.981	0.086
NEK2	ANAPC10	0.98	0.182
ANAPC15	CDC26	0.979	0.172	mutually_exclusive (O43684)
NEK2	ANAPC1	0.979	0.19
RRM2	ANAPC13	0.979	0.056
NEK2	CFAP97	0.979	0.18
CDC20	CDC27	0.978	0.166	structurally_consistent (Q9UM13)
FZR1	ANAPC15	0.978	0.2	mutually_exclusive (O43684)
CDC20	ANAPC4	0.978	0.052
ANAPC4	CFAP97	0.978	0.08
CDC20	ANAPC15	0.977	0.148
ANAPC10	CFAP97	0.977	0.078
NEK2	CDC27	0.977	0.084
CDC20	ANAPC10	0.976	0.254	structurally_consistent (dimer)
ANAPC5	CFAP97	0.975	0.11
CDC16	NEK2	0.974	0.202
BUB1B	ANAPC16	0.974	0.298
GNPTAB	ANAPC4	0.973	0.094
FZR1	BUB1B	0.971	0.146	mutually_exclusive (O43684)
CDC20	NEK2	0.97	0.2128875
NEK2	ANAPC4	0.967	0.07
FZR1	GNPTAB	0.967	0.134
GNPTAB	CDC27	0.967	0.048
GNPTAB	ANAPC10	0.966	0.128
NEK2	FBXO5	0.966	0.178
ANAPC15	FBXO5	0.966	0.154
CDC23	NEK2	0.964	0.116
ANAPC15	ANAPC13	0.962	0.2
RRM2	ANAPC10	0.962	0.148
BUB1B	ANAPC10	0.961	0.178	mutually_exclusive (O43684)
ANAPC7	CFAP97	0.96	0.074
BUB1B	CDC16	0.957	0.1
ANAPC15	ANAPC10	0.956	0.274	mutually_exclusive (O43684)
CDC20	ANAPC7	0.953	0.052
BUB1B	FBXO5	0.952	0.198
GNPTAB	ANAPC1	0.947	0.102
ANAPC15	CFAP97	0.944	0.152
RRM2	BUB1B	0.937	0.406
GNPTAB	CDC20	0.936	0.180560283688
RRM2	ANAPC7	0.933	0.044
RRM2	ANAPC15	0.931	0.138
ANAPC15	NEK2	0.93	0.118
RRM2	ANAPC4	0.93	0.102
GNPTAB	ANAPC15	0.926	0.114
RRM2	GNPTAB	0.921	0.084
BUB1B	ANAPC5	0.92	0.070219858156
BUB1B	CDC27	0.912	0.118
BUB1B	ANAPC15	0.905	0.192	mutually_exclusive (O43684)
CDC20	CFAP97	0.904	0.158560283688
BUB1B	ANAPC13	0.903	0.168320754717
RRM2	ANAPC5	0.899	0.094
RRM2	CDC20	0.894	0.324
BUB1B	ANAPC1	0.842	0.224
BUB1B	NEK2	0.811	0.176
GNPTAB	BUB1B	0.795	0.078
GNPTAB	NEK2	0.785	0.32
GNPTAB	CFAP97	0.785	0.11
BUB1B	ANAPC7	0.782	0.072
BUB1B	CFAP97	0.772	0.086
BUB1B	ANAPC4	0.746	0.086
RRM2	ANAPC1	0.714	0.08
RRM2	NEK2	0.648	0.116
RRM2	CFAP97	0.528	0.078

Related Complexes

Genename	Complexes
RRM2	huMAP3_03279.1 huMAP3_03388.1 huMAP3_07989.1 huMAP3_11033.1 huMAP3_12747.1
GNPTAB	huMAP3_03378.1 huMAP3_03388.1 huMAP3_11112.1 huMAP3_11412.1
BUB1B	huMAP3_03388.1 huMAP3_12747.1
ANAPC16	huMAP3_03388.1 huMAP3_12747.1
FZR1	huMAP3_00732.1 huMAP3_03388.1 huMAP3_07079.1 huMAP3_09021.1 huMAP3_12747.1 huMAP3_13744.1
CDC20	huMAP3_03388.1 huMAP3_12747.1
ANAPC15	huMAP3_03388.1 huMAP3_12747.1
CDC23	huMAP3_03388.1 huMAP3_12747.1
ANAPC13	huMAP3_03388.1 huMAP3_12747.1
CDC16	huMAP3_03388.1 huMAP3_12097.1 huMAP3_12747.1
NEK2	huMAP3_03388.1 huMAP3_12747.1
ANAPC10	huMAP3_03388.1 huMAP3_12747.1
CDC26	huMAP3_03388.1 huMAP3_12747.1
ANAPC7	huMAP3_03388.1 huMAP3_12747.1
ANAPC4	huMAP3_03388.1 huMAP3_12747.1
ANAPC1	huMAP3_03388.1 huMAP3_12747.1
CDC27	huMAP3_03388.1 huMAP3_12747.1
ANAPC5	huMAP3_03388.1 huMAP3_12747.1
CFAP97	huMAP3_03388.1 huMAP3_12747.1 huMAP3_15205.1
ANAPC2	huMAP3_03388.1 huMAP3_12747.1
FBXO5	huMAP3_03388.1 huMAP3_12747.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_03388.1

Complex Portal: CPX-23522