hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03410.1
Complex Portal: CPX-22934
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM13C | Protein FAM13C | 5 | UniProt NCBI |
| AHCYL1 | S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2) | 5 | UniProt NCBI |
| PITX2 | Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin) | 5 | UniProt NCBI |
| AHCYL2 | Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00270 | 0.0025855951209 | 0.5 | AHCYL2 AHCYL1 | Cysteine and methionine metabolism |
| WP:WP2525 | 0.00377411060353 | 0.5 | AHCYL2 AHCYL1 | Trans sulfuration one carbon metabolism and related pathways |
| GO:0033353 | 0.00842684400117 | 0.5 | AHCYL2 AHCYL1 | S-adenosylmethionine cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AHCYL1 | AHCYL2 | 0.999 | 0.236 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| FAM13C | AHCYL2 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PITX2 | AHCYL2 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| AHCYL1 | FAM13C | 0.939 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| AHCYL1 | PITX2 | 0.707 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes