hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_03435.1

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
IFT140	Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)	5	UniProt NCBI
IFT43	Intraflagellar transport protein 43 homolog	5	UniProt NCBI
WDR35	WD repeat-containing protein 35 (Intraflagellar transport protein 121 homolog)	5	UniProt NCBI
IFT122	Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140)	5	UniProt NCBI
WDR19	WD repeat-containing protein 19 (Intraflagellar transport 144 homolog)	5	UniProt NCBI
IFTAP	Intraflagellar transport-associated protein (Protein HEPIS)	3	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0030991	3.2413958192e-13	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	intraciliary transport particle A
CORUM:6585	4.80104919782e-12	0.666666666667	IFT140 IFT122 WDR19 WDR35	Intraflagellar transport complex A
WP:WP4532	6.24974716144e-12	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Intraflagellar transport proteins binding to dynein
GO:0035721	6.95001783241e-11	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	intraciliary retrograde transport
REAC:R-HSA-5620924	4.65360810562e-10	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Intraflagellar transport
WP:WP5234	1.42623518968e-09	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Bardet Biedl syndrome
GO:0030990	1.81606603046e-09	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	intraciliary transport particle
HP:0008905	4.92898512047e-09	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Rhizomelia
WP:WP4536	5.23603068389e-09	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Genes related to primary cilium development based on CRISPR
HP:0008873	4.29803835863e-08	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Disproportionate short-limb short stature
GO:0042073	4.58614910437e-08	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	intraciliary transport
WP:WP4803	5.54557903312e-08	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Ciliopathies
GO:0097542	6.58565753718e-08	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	ciliary tip
HP:0000774	9.65286586915e-08	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Narrow chest
HP:0003498	1.2126052463e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Disproportionate short stature
HP:0005257	2.27149801615e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Thoracic hypoplasia
REAC:R-HSA-5617833	3.74471976961e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Cilium Assembly
HP:0010306	5.52747893676e-07	0.666666666667	IFT140 IFT122 WDR19 WDR35	Short thorax
HP:0000691	6.14182442931e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Microdontia
HP:0009803	7.42377744679e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Short phalanx of finger
HP:0000679	7.46166611169e-07	0.666666666667	IFT43 IFT122 WDR19 WDR35	Taurodontia
HP:0011071	7.46166611169e-07	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal permanent molar morphology
HP:0001363	7.65678883854e-07	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Craniosynostosis
HP:0011070	9.00661990159e-07	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal molar morphology
HP:0011077	9.86331068136e-07	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormality of molar
HP:0006479	1.07796447757e-06	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal dental pulp morphology
HP:0006486	1.07796447757e-06	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal dental root morphology
HP:0000268	1.09377697467e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Dolichocephaly
HP:0000269	1.28021006661e-06	0.666666666667	IFT43 IFT122 WDR19 WDR35	Prominent occiput
HP:0009767	1.5670211959e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/Hypoplasia of the phalanges of the hand
HP:0000944	1.74155061016e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal metaphysis morphology
HP:0000773	2.21755710014e-06	0.666666666667	IFT140 IFT122 WDR35 IFT43	Short ribs
REAC:R-HSA-1852241	2.47115045635e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Organelle biogenesis and maintenance
HP:0009826	3.21680362051e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Limb undergrowth
HP:0008499	5.21207949413e-06	0.666666666667	IFT43 IFT122 WDR19 WDR35	High hypermetropia
HP:0006482	5.90761647521e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal dental morphology
REAC:R-HSA-5610787	6.85992153937e-06	0.666666666667	IFT140 IFT122 WDR19 WDR35	Hedgehog 'off' state
HP:0009381	9.25651290097e-06	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Short finger
HP:0002983	9.52382922551e-06	0.666666666667	IFT140 WDR19 WDR35 IFT43	Micromelia
HP:0000772	1.11183549237e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal rib morphology
GO:0031503	1.258414027e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	protein-containing complex localization
REAC:R-HSA-5358351	1.67659998e-05	0.666666666667	IFT140 IFT122 WDR19 WDR35	Signaling by Hedgehog
HP:0006265	1.76739828051e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/Hypoplasia of fingers
GO:0010970	1.93005700328e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	transport along microtubule
HP:0011217	2.1709105889e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal shape of the occiput
HP:0009882	2.26206838432e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Short distal phalanx of finger
HP:0008070	2.35393522854e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Sparse hair
HP:0012294	2.35606190872e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal occipital bone morphology
HP:0011329	2.42767191814e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of cranial sutures
HP:0001156	2.50324136667e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Brachydactyly
HP:0001547	2.66001423518e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal rib cage morphology
HP:0009835	2.76156062683e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Aplasia/Hypoplasia of the distal phalanges of the hand
HP:0006712	3.21716924889e-05	0.666666666667	IFT140 IFT122 WDR35 IFT43	Aplasia/Hypoplasia of the ribs
HP:0004442	3.36277715305e-05	0.5	IFT43 WDR19 IFT122	Sagittal craniosynostosis
GO:0005929	3.40829569636e-05	1.0	WDR19 IFT122 IFT43 IFT140 IFTAP WDR35	cilium
GO:0099111	3.50374175094e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	microtubule-based transport
HP:0000083	3.51531007428e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Renal insufficiency
HP:0004209	3.66837991217e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Clinodactyly of the 5th finger
HP:0009179	3.72056880074e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Deviation of the 5th finger
HP:0002007	3.82672469355e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Frontal bossing
HP:0000687	3.86317345518e-05	0.666666666667	IFT140 IFT122 WDR35 IFT43	Widely spaced teeth
HP:0001159	3.8807016949e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Syndactyly
HP:0000968	3.92263544242e-05	0.5	IFT43 IFT122 WDR35	Ectodermal dysplasia
HP:0011218	3.99047900799e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal shape of the frontal region
HP:0430000	4.04628948337e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal frontal bone morphology
HP:0000973	4.29464917268e-05	0.666666666667	IFT140 WDR19 WDR35 IFT43	Cutis laxa
HP:0003774	4.29464917268e-05	0.666666666667	IFT140 IFT122 WDR19 IFT43	Stage 5 chronic kidney disease
HP:0001407	5.22168897407e-05	0.5	IFT140 WDR19 IFT122	Hepatic cysts
HP:0040019	5.30000762825e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Finger clinodactyly
HP:0000232	5.62183067184e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Everted lower lip vermilion
HP:0000293	5.80703630675e-05	0.666666666667	IFT140 IFT122 WDR19 WDR35	Full cheeks
HP:0001395	5.99676998675e-05	0.666666666667	IFT140 IFT122 WDR19 WDR35	Hepatic fibrosis
HP:0100259	5.99676998675e-05	0.666666666667	IFT140 WDR19 WDR35 IFT43	Postaxial polydactyly
HP:0000601	5.99676998675e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Hypotelorism
HP:0000766	6.26877314152e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal sternum morphology
HP:0000235	6.26877314152e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the fontanelles or cranial sutures
GO:0030705	6.51851913963e-05	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	cytoskeleton-dependent intracellular transport
HP:0008388	8.90924557824e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal toenail morphology
HP:0009832	9.17027073507e-05	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal distal phalanx morphology of finger
HP:0004207	0.000101662063112	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal 5th finger morphology
GO:0061512	0.000106291409046	0.666666666667	IFT140 IFT122 WDR19 WDR35	protein localization to cilium
HP:0005927	0.000117817736994	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/hypoplasia involving bones of the hand
HP:0004097	0.000120475158955	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Deviation of finger
HP:0012472	0.00013813645411	0.666666666667	IFT43 IFT122 WDR19 WDR35	Eclabion
HP:0004349	0.000138937389081	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Reduced bone mineral density
HP:0009484	0.00015299090284	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Deviation of the hand or of fingers of the hand
HP:0006711	0.000153040914143	0.666666666667	IFT140 IFT122 WDR35 IFT43	Aplasia/Hypoplasia involving bones of the thorax
HP:0008067	0.000156947710561	0.666666666667	IFT140 WDR19 WDR35 IFT43	Abnormally lax or hyperextensible skin
HP:0006496	0.000164686603855	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/hypoplasia involving bones of the upper limbs
HP:0030084	0.000164686603855	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Clinodactyly
HP:0000090	0.000176135758605	0.5	IFT140 WDR19 IFT43	Nephronophthisis
HP:0001231	0.000177611776856	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal fingernail morphology
HP:0012622	0.000181977153209	0.666666666667	IFT140 IFT122 WDR19 IFT43	Chronic kidney disease
HP:0030799	0.00022859990461	0.5	IFT140 IFT122 IFT43	Scaphocephaly
HP:0006706	0.00022859990461	0.5	IFT140 WDR19 IFT122	Cystic liver disease
HP:0011927	0.000234335086831	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Short digit
HP:0004348	0.000253142887328	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of bone mineral density
HP:0002612	0.000268794104831	0.5	IFT140 WDR19 WDR35	Congenital hepatic fibrosis
HP:0000682	0.000269185172277	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal dental enamel morphology
HP:0000286	0.000286256639547	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Epicanthus
HP:0006101	0.00028733406656	0.666666666667	IFT43 IFT122 WDR19 WDR35	Finger syndactyly
HP:3000050	0.00036179605176	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal odontoid tissue morphology
HP:0045060	0.00039284272989	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/hypoplasia involving bones of the extremities
HP:0000668	0.000400032634721	0.666666666667	IFT43 IFT122 WDR19 WDR35	Hypodontia
HP:0005918	0.000432176588807	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal finger phalanx morphology
HP:0010647	0.000467390235865	0.666666666667	IFT140 WDR19 WDR35 IFT43	Abnormal elasticity of skin
HP:0012211	0.000474588206171	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal renal physiology
HP:0000178	0.000504080307199	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal lower lip morphology
HP:0011849	0.000542134971941	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal bone ossification
HP:0009815	0.000573995109675	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/hypoplasia of the extremities
HP:0004426	0.000605208682095	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormal cheek morphology
GO:0007018	0.000624476368572	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	microtubule-based movement
GO:0060271	0.000659970192201	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	cilium assembly
HP:0010442	0.000661105912226	0.666666666667	IFT140 WDR19 WDR35 IFT43	Polydactyly
HP:0000540	0.000672732345354	0.666666666667	IFT43 IFT122 WDR19 WDR35	Hypermetropia
HP:0100957	0.000727842944018	0.5	IFT140 WDR19 IFT43	Abnormal renal medulla morphology
HP:0011314	0.000727873953521	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal long bone morphology
HP:0006494	0.000771326645447	0.666666666667	IFT140 IFT122 WDR19 WDR35	Aplasia/Hypoplasia involving bones of the feet
GO:0044782	0.000939927808533	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	cilium organization
HP:0003330	0.000961121315124	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal bone structure
HP:0000939	0.000984794049706	0.666666666667	IFT43 IFT122 WDR19 WDR35	Osteoporosis
HP:0000940	0.00131506983485	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal diaphysis morphology
HP:0000767	0.00139398016067	0.666666666667	IFT43 IFT122 WDR19 WDR35	Pectus excavatum
HP:0011362	0.00145274392888	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal hair quantity
HP:0012440	0.00146741733922	0.5	IFT140 WDR19 WDR35	Abnormal biliary tract morphology
HP:0410042	0.00149218749136	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal liver morphology
HP:0002213	0.00160231496954	0.5	IFT43 IFT122 WDR35	Fine hair
HP:0006644	0.00161951205762	0.333333333333	WDR35 WDR19	Thoracic dysplasia
HP:0000765	0.00183941883667	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal thorax morphology
HP:0011061	0.00204945939855	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormality of dental structure
HP:0009804	0.00224410228317	0.666666666667	IFT43 IFT122 WDR19 WDR35	Tooth agenesis
HP:0001080	0.00240122360395	0.5	IFT140 WDR19 WDR35	Biliary tract abnormality
HP:0001162	0.00249319307056	0.5	IFT140 WDR19 WDR35	Postaxial hand polydactyly
HP:0006493	0.00251421996371	0.666666666667	IFT140 IFT122 WDR19 WDR35	Aplasia/hypoplasia involving bones of the lower limbs
HP:0004297	0.00267436793474	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormality of the biliary system
HP:0000164	0.00267809056162	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the dentition
HP:0002683	0.00275841306414	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal calvaria morphology
HP:0001105	0.00288444095262	0.5	IFT140 WDR19 IFT43	Retinal atrophy
HP:0006483	0.00339206501528	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal number of teeth
HP:0005922	0.00383825241604	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal hand morphology
HP:0000692	0.00384317259801	0.666666666667	IFT140 IFT122 WDR35 IFT43	Tooth malposition
HP:0000639	0.00394511883564	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Nystagmus
WP:WP4352	0.00400681842466	0.5	IFT140 IFT122 IFT43	Ciliary landscape
HP:0012547	0.00425698750482	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal involuntary eye movements
HP:0011277	0.00434960001953	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the urinary system physiology
HP:0001392	0.00442010530108	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the liver
GO:0120031	0.00450571144333	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	plasma membrane bounded cell projection assembly
HP:0000545	0.0046263330141	0.666666666667	IFT43 IFT122 WDR19 WDR35	Myopia
HP:0100886	0.00496538568106	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of globe location
HP:0007843	0.00500109820736	0.5	IFT140 WDR19 IFT43	Attenuation of retinal blood vessels
GO:0030031	0.00509483152423	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	cell projection assembly
HP:0012210	0.00517642268402	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal renal morphology
HP:0040070	0.00530098811513	0.666666666667	IFT140 IFT122 WDR19 IFT43	Abnormal upper limb bone morphology
HP:0001799	0.00593279372985	0.333333333333	IFT43 IFT122	Short nail
HP:0030151	0.00593279372985	0.333333333333	IFT140 WDR35	Cholangitis
HP:0000463	0.00680101690504	0.666666666667	IFT43 IFT122 WDR19 WDR35	Anteverted nares
HP:0002088	0.00686160531048	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal lung morphology
HP:0000290	0.00748705795004	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the forehead
HP:0004299	0.00776768683012	0.666666666667	IFT140 IFT122 WDR19 WDR35	Hernia of the abdominal wall
HP:0005288	0.0078404361426	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal nostril morphology
HP:0001597	0.0079136910806	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormality of the nail
HP:0010866	0.00798745393246	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abdominal wall defect
HP:0009115	0.00811857195519	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Aplasia/hypoplasia involving the skeleton
HP:0001167	0.00819556560378	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal finger morphology
HP:0001773	0.00857286967155	0.5	IFT140 WDR19 WDR35	Short foot
HP:0000159	0.00895634608406	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal lip morphology
HP:0000431	0.00923862134853	0.666666666667	IFT140 IFT122 WDR19 WDR35	Wide nasal bridge
HP:0004298	0.0107218211673	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormality of the abdominal wall
HP:0006703	0.0113637882169	0.5	IFT140 WDR19 WDR35	Aplasia/Hypoplasia of the lungs
HP:0002012	0.0113787764877	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the abdominal organs
HP:0001595	0.0120457334662	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal hair morphology
HP:0001382	0.0123751293622	0.666666666667	IFT43 IFT122 WDR19 WDR35	Joint hypermobility
HP:0000506	0.0138111776458	0.5	IFT43 IFT122 WDR35	Telecanthus
HP:0000492	0.0145979030629	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal eyelid morphology
HP:0000429	0.0146705398092	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormal morphology of the nasal alae
HP:0100790	0.0149045236961	0.666666666667	IFT140 IFT122 WDR19 WDR35	Hernia
HP:0004322	0.0155378546416	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Short stature
HP:0012252	0.0159270158081	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal respiratory system morphology
GO:0120025	0.0160788696948	1.0	WDR19 IFT122 IFT43 IFT140 IFTAP WDR35	plasma membrane bounded cell projection
HP:0000077	0.0163907734884	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the kidney
GO:0042995	0.0170600837211	1.0	WDR19 IFT122 IFT43 IFT140 IFTAP WDR35	cell projection
HP:0002205	0.0175320772209	0.666666666667	IFT140 IFT122 WDR19 WDR35	Recurrent respiratory infections
HP:0010935	0.0182080116735	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the upper urinary tract
HP:0001161	0.0182726158894	0.5	IFT140 WDR19 WDR35	Hand polydactyly
HP:0005105	0.0185751109679	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal nasal morphology
HP:0002652	0.0186233915395	0.5	IFT140 WDR19 WDR35	Skeletal dysplasia
HP:0000319	0.0186233915395	0.5	IFT140 WDR19 WDR35	Smooth philtrum
HP:0002644	0.0197536366037	0.666666666667	IFT140 WDR19 WDR35 IFT43	Abnormal pelvic girdle bone morphology
HP:0011138	0.0204198186076	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal skin adnexa morphology
HP:0000309	0.0209395955205	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormal midface morphology
HP:0002240	0.0212441588114	0.666666666667	IFT140 IFT122 WDR19 WDR35	Hepatomegaly
HP:0010719	0.0223788473695	0.5	IFT43 IFT122 WDR35	Abnormality of hair texture
HP:0001970	0.0226111656051	0.333333333333	IFT122 WDR19	Tubulointerstitial nephritis
HP:0009836	0.0226111656051	0.333333333333	IFT122 WDR19	Broad distal phalanx of finger
HP:0003549	0.0226657898986	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of connective tissue
HP:0011297	0.0228396399634	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal digit morphology
HP:0001760	0.0229269607293	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal foot morphology
HP:0000002	0.0229269607293	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of body height
HP:0000662	0.0261590153267	0.5	IFT140 WDR19 IFT43	Nyctalopia
HP:0030669	0.0286721248803	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal ocular adnexa morphology
HP:0001155	0.0291980155437	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the hand
HP:0000539	0.0297854763042	0.666666666667	IFT43 IFT122 WDR19 WDR35	Abnormality of refraction
HP:0032039	0.0302727333936	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the ocular adnexa
HP:0001780	0.0326351056455	0.666666666667	IFT140 IFT122 WDR19 IFT43	Abnormal toe morphology
HP:0000315	0.032863784458	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the orbital region
HP:0003271	0.0354575661861	0.666666666667	IFT140 IFT122 WDR19 WDR35	Visceromegaly
HP:4000059	0.0365652768554	0.5	IFT140 WDR19 WDR35	Abnormal lung development
HP:0009997	0.0399718389151	0.5	IFT140 WDR19 WDR35	Duplication of phalanx of hand
HP:0009142	0.0405591774535	0.5	IFT140 WDR19 WDR35	Duplication of bones involving the upper extremities
HP:0004275	0.0405591774535	0.5	IFT140 WDR19 WDR35	Duplication of hand bones
HP:0011947	0.0408888963229	0.666666666667	IFT140 IFT122 WDR19 WDR35	Respiratory tract infection
HP:0000366	0.0412870242376	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the nose
HP:0040069	0.0418928749121	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormal lower limb bone morphology
HP:0002817	0.0437114869583	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of the upper limb
HP:0040068	0.0445935923605	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of limb bone
HP:0002813	0.0445935923605	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormal limb bone morphology
HP:0001770	0.0454639361427	0.5	IFT140 WDR19 IFT43	Toe syndactyly
HP:0001737	0.0467604957305	0.333333333333	IFT140 WDR19	Pancreatic cysts
HP:0008046	0.0480563748242	0.5	IFT140 WDR19 IFT43	Abnormal retinal vascular morphology
HP:0000496	0.0495393048868	0.833333333333	IFT140 IFT122 WDR19 WDR35 IFT43	Abnormality of eye movement
HP:0001438	0.0497272491045	0.666666666667	IFT140 IFT122 WDR19 WDR35	Abnormal abdomen morphology

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
IFT43	WDR35	1.0	0.184	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT43	WDR19	1.0	0.154	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT140	IFT43	1.0	0.192	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT43	IFT122	1.0	0.224	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
WDR35	IFTAP	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT122	WDR19	0.999	0.188	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM
IFT43	IFTAP	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT140	IFT122	0.999	0.24	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM
IFT122	IFTAP	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
IFT140	IFTAP	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
WDR35	IFT122	0.998	0.18	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM
WDR19	IFTAP	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
WDR35	WDR19	0.998	0.208	bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
IFT140	WDR35	0.997	0.206	bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM
IFT140	WDR19	0.994	0.262	bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM

Related Complexes

Genename	Complexes
IFT140	huMAP3_03435.1 huMAP3_12868.1
IFT43	huMAP3_03435.1 huMAP3_05176.1 huMAP3_12868.1
WDR35	huMAP3_03435.1 huMAP3_12868.1
IFT122	huMAP3_03435.1 huMAP3_12868.1
WDR19	huMAP3_03435.1 huMAP3_12868.1
IFTAP	huMAP3_03435.1 huMAP3_12868.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_03435.1