hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03516.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COMMD5 | COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG) | 4 | UniProt NCBI |
| RANBP1 | Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1) | 5 | UniProt NCBI |
| ATAD3C | ATPase family AAA domain-containing protein 3C | 2 | UniProt NCBI |
| COMMD6 | COMM domain-containing protein 6 | 5 | UniProt NCBI |
| TFDP1 | Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1) | 5 | UniProt NCBI |
| COMMD1 | COMM domain-containing protein 1 (Protein Murr1) | 5 | UniProt NCBI |
| VPS35L | VPS35 endosomal protein-sorting factor-like (Esophageal cancer-associated protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6645 | 1.37265258548e-09 | 0.571428571429 | COMMD5 VPS35L COMMD1 COMMD6 | CCC complex |
| CORUM:6639 | 2.61965734068e-09 | 0.571428571429 | COMMD5 VPS35L COMMD1 COMMD6 | CCC-Wash (WASH1, FAM21C) complex |
| CORUM:7133 | 6.1565588648e-05 | 0.285714285714 | COMMD6 COMMD1 | CCDC93-COMMD1-COMMD6 complex |
| CORUM:7134 | 6.1565588648e-05 | 0.285714285714 | COMMD1 VPS35L | COMMD1-CCDC93-C16orf62 complex |
| CORUM:7131 | 0.000123103089524 | 0.285714285714 | COMMD1 VPS35L | COMMD1-CCDC22-CCDC93-C16orf62 complex |
| REAC:R-HSA-8951664 | 0.0233324089042 | 0.428571428571 | COMMD5 COMMD1 COMMD6 | Neddylation |
| WP:WP5345 | 0.039968890476 | 0.285714285714 | ATAD3C COMMD1 | 1p36 copy number variation syndrome |
| CORUM:680 | 0.0499958217778 | 0.142857142857 | RANBP1 | RANBMP-CD39 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| COMMD5 | VPS35L | 1.0 | 0.288 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| COMMD1 | VPS35L | 1.0 | 0.138 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| COMMD5 | COMMD6 | 1.0 | 0.266 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| COMMD6 | VPS35L | 1.0 | 0.172 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| COMMD6 | TFDP1 | 0.999 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| COMMD5 | COMMD1 | 0.999 | 0.206 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| COMMD6 | COMMD1 | 0.999 | 0.812 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| TFDP1 | COMMD1 | 0.999 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| COMMD5 | TFDP1 | 0.994 | 0.05 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| RANBP1 | COMMD5 | 0.986 | 0.08 | hein_WMM bioplex3_HEK293 bioplex_WMM hein () |
| TFDP1 | VPS35L | 0.984 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only |
| ATAD3C | COMMD1 | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RANBP1 | COMMD1 | 0.974 | 0.068 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| RANBP1 | VPS35L | 0.965 | 0.04 | hein_WMM bioplex_WMM hein () gupta_WMM |
| RANBP1 | COMMD6 | 0.91 | 0.076 | hein_WMM bioplex_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| ATAD3C | COMMD6 | 0.824 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ATAD3C | COMMD5 | 0.41 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATAD3C | VPS35L | 0.209 | bioplex_WMM bioplex3_WMM WMM_only | |
| ATAD3C | TFDP1 | 0.056 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RANBP1 | TFDP1 | 0.003 | 0.102 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| RANBP1 | ATAD3C | 0.001 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes