hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03527.1
Complex Portal: CPX-11257
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LIFR | Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) | 5 | UniProt NCBI |
| ZNRF3 | E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3) | 5 | UniProt NCBI |
| PAQR3 | Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG) | 5 | UniProt NCBI |
| MARCHF1 | E3 ubiquitin-protein ligase MARCHF1 (EC 2.3.2.27) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I) (RING finger protein 171) (RING-type E3 ubiquitin transferase MARCHF1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5579 | 0.049938562206 | 0.25 | LIFR | CNTF-CNTFR-gp130-LIFR complex |
| CORUM:5582 | 0.049938562206 | 0.25 | LIFR | LIFR-LIF-gp130 complex |
| CORUM:7515 | 0.049938562206 | 0.25 | PAQR3 | PAQR3-SCAP-complex |
| CORUM:7516 | 0.049938562206 | 0.25 | PAQR3 | PAQR3-SREBF2 complex |
| CORUM:7521 | 0.049938562206 | 0.25 | PAQR3 | INSIG1-PAQR3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MARCHF1 | PAQR3 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZNRF3 | MARCHF1 | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| LIFR | MARCHF1 | 0.951 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZNRF3 | PAQR3 | 0.079 | bioplex3_WMM WMM_only | ||
| LIFR | PAQR3 | 0.076 | bioplex3_WMM WMM_only | ||
| LIFR | ZNRF3 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes