hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03532.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACTG2 | Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form] | 5 | UniProt NCBI |
| CAPS | Calcyphosin (Calcyphosine) | 5 | UniProt NCBI |
| ANTXR2 | Anthrax toxin receptor 2 (Capillary morphogenesis gene 2 protein) (CMG-2) | 5 | UniProt NCBI |
| IGSF8 | Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316) | 5 | UniProt NCBI |
| CD9 | CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9) | 5 | UniProt NCBI |
| SLC7A7 | Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1) | 5 | UniProt NCBI |
| CD81 | CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0014905 | 0.0294899169624 | 0.285714285714 | CD81 CD9 | myoblast fusion involved in skeletal muscle regeneration |
| HP:0002718 | 0.0356200251306 | 0.428571428571 | ANTXR2 SLC7A7 CD81 | Recurrent bacterial infections |
| CORUM:2370 | 0.0499958217778 | 0.142857142857 | CD9 | ITGA2B-ITGB3-CD9 complex |
| CORUM:2770 | 0.0499958217778 | 0.142857142857 | CD9 | ITGA6-ITGB4-CD9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IGSF8 | SLC7A7 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CD9 | IGSF8 | 0.997 | 0.028 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ACTG2 | IGSF8 | 0.996 | 0.156 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CD81 | IGSF8 | 0.989 | 0.044 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CAPS | IGSF8 | 0.986 | 0.078 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ANTXR2 | IGSF8 | 0.962 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CAPS | ACTG2 | 0.908 | 0.138 | bioplex3_WMM WMM_only |
| CAPS | SLC7A7 | 0.908 | bioplex3_WMM WMM_only | |
| CD81 | ACTG2 | 0.902 | 0.056 | bioplex3_WMM WMM_only |
| ACTG2 | SLC7A7 | 0.902 | bioplex3_WMM WMM_only | |
| CD81 | SLC7A7 | 0.902 | bioplex3_WMM WMM_only | |
| CD81 | CAPS | 0.899 | 0.104 | bioplex3_WMM WMM_only |
| ANTXR2 | SLC7A7 | 0.214 | bioplex3_WMM WMM_only | |
| ACTG2 | ANTXR2 | 0.214 | 0.096 | bioplex3_WMM WMM_only |
| CD9 | ANTXR2 | 0.204 | 0.162 | bioplex_WMM bioplex3_WMM WMM_only |
| CD9 | SLC7A7 | 0.162 | bioplex3_WMM WMM_only | |
| CD9 | ACTG2 | 0.162 | 0.166 | bioplex3_WMM WMM_only |
| CD81 | ANTXR2 | 0.146 | 0.16 | bioplex3_WMM WMM_only |
| CD81 | CD9 | 0.141 | 0.198 | bioplex3_WMM WMM_only |
| CAPS | CD9 | 0.096 | 0.126 | bioplex3_WMM WMM_only |
| CAPS | ANTXR2 | 0.051 | 0.106 | bioplex3_WMM WMM_only |
Related Complexes