hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03539.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HS3ST2 | Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2) | 5 | UniProt NCBI |
| HS3ST4 | Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2022928 | 0.000645911942305 | 1.0 | HS3ST2 HS3ST4 | HS-GAG biosynthesis |
| REAC:R-HSA-1638091 | 0.00209323314636 | 1.0 | HS3ST2 HS3ST4 | Heparan sulfate/heparin (HS-GAG) metabolism |
| WP:WP702 | 0.00384988683014 | 1.0 | HS3ST2 HS3ST4 | Metapathway biotransformation Phase I and II |
| GO:0008467 | 0.00468200720083 | 1.0 | HS3ST2 HS3ST4 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
| REAC:R-HSA-1630316 | 0.010244026704 | 1.0 | HS3ST2 HS3ST4 | Glycosaminoglycan metabolism |
| GO:0034483 | 0.0365196561665 | 1.0 | HS3ST2 HS3ST4 | heparan sulfate sulfotransferase activity |
| GO:0030201 | 0.0365196561665 | 1.0 | HS3ST2 HS3ST4 | heparan sulfate proteoglycan metabolic process |
| KEGG:00534 | 0.0498575241799 | 0.5 | HS3ST2 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HS3ST2 | HS3ST4 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| HS3ST2 | huMAP3_02857.1 huMAP3_03539.1 huMAP3_08299.1 huMAP3_11760.1 huMAP3_12094.1 |
| HS3ST4 | huMAP3_03326.1 huMAP3_03539.1 huMAP3_08299.1 huMAP3_10878.1 huMAP3_11760.1 huMAP3_12094.1 |