hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03555.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2) | 5 | UniProt NCBI |
| IRAK2 | Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4136 | 0.00022473634564 | 1.0 | TIRAP IRAK2 | Fibrin complement receptor 3 signaling pathway |
| KEGG:05152 | 0.001720800216 | 1.0 | TIRAP IRAK2 | Tuberculosis |
| REAC:R-HSA-166058 | 0.00762962122326 | 1.0 | TIRAP IRAK2 | MyD88:MAL(TIRAP) cascade initiated on plasma membrane |
| REAC:R-HSA-168188 | 0.00762962122326 | 1.0 | TIRAP IRAK2 | Toll Like Receptor TLR6:TLR2 Cascade |
| REAC:R-HSA-181438 | 0.00795599471791 | 1.0 | TIRAP IRAK2 | Toll Like Receptor 2 (TLR2) Cascade |
| REAC:R-HSA-168179 | 0.00795599471791 | 1.0 | TIRAP IRAK2 | Toll Like Receptor TLR1:TLR2 Cascade |
| REAC:R-HSA-166016 | 0.0128208394262 | 1.0 | TIRAP IRAK2 | Toll Like Receptor 4 (TLR4) Cascade |
| REAC:R-HSA-168898 | 0.0171064139006 | 1.0 | TIRAP IRAK2 | Toll-like Receptor Cascades |
| GO:0002755 | 0.0365196561665 | 1.0 | TIRAP IRAK2 | MyD88-dependent toll-like receptor signaling pathway |
| CORUM:1944 | 0.0499419797295 | 0.5 | IRAK2 | IRAK1-IRAK2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TIRAP | IRAK2 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TIRAP | huMAP3_03555.1 huMAP3_06152.1 huMAP3_13697.1 huMAP3_14870.1 huMAP3_15080.1 |
| IRAK2 | huMAP3_03555.1 huMAP3_09006.1 huMAP3_13697.1 huMAP3_14870.1 huMAP3_15080.1 |