hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03593.1
Complex Portal: CPX-11811
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CD14 | Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form] | 5 | UniProt NCBI |
| SERPINE1 | Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5115 | 0.00618663406037 | 1.0 | SERPINE1 CD14 | Network map of SARS CoV 2 signaling pathway |
| REAC:R-HSA-166020 | 0.0249718442457 | 0.5 | CD14 | Transfer of LPS from LBP carrier to CD14 |
| WP:WP4146 | 0.0435328773163 | 0.5 | CD14 | Macrophage markers |
| HP:0040184 | 0.0499436884913 | 0.5 | SERPINE1 | Oral bleeding |
| HP:0040230 | 0.0499436884913 | 0.5 | SERPINE1 | Decreased level of tissue plasminogen activator |
| HP:0040245 | 0.0499436884913 | 0.5 | SERPINE1 | Reduced alpha-2-antiplasmin activity |
| HP:0040248 | 0.0499436884913 | 0.5 | SERPINE1 | Reduced plasminogen activator inhibitor 1 activity |
| HP:0040249 | 0.0499436884913 | 0.5 | SERPINE1 | Reduced plasminogen activator inhibitor 1 antigen |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CD14 | SERPINE1 | 0.997 | 0.304 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CD14 | huMAP3_03593.1 huMAP3_14537.1 |
| SERPINE1 | huMAP3_03593.1 |