hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03610.1
Complex Portal: CPX-12263
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RPL35A | Large ribosomal subunit protein eL33 (60S ribosomal protein L35a) (Cell growth-inhibiting gene 33 protein) | 5 | UniProt NCBI |
| CNBP | CCHC-type zinc finger nucleic acid binding protein (Cellular nucleic acid-binding protein) (CNBP) (Zinc finger protein 9) | 5 | UniProt NCBI |
| ZFP62 | Zinc finger protein 62 homolog (Zfp-62) | 3 | UniProt NCBI |
| RPL34 | Large ribosomal subunit protein eL34 (60S ribosomal protein L34) | 5 | UniProt NCBI |
| MMTAG2 | Multiple myeloma tumor-associated protein 2 (hMMTAG2) | 5 | UniProt NCBI |
| NCL | Nucleolin (Protein C23) | 5 | UniProt NCBI |
| RPL27A | Large ribosomal subunit protein uL15 (60S ribosomal protein L27a) | 5 | UniProt NCBI |
| H2AC21 | Histone H2A type 2-B (H2A-clustered histone 21) | 5 | UniProt NCBI |
| RPL21 | Large ribosomal subunit protein eL21 (60S ribosomal protein L21) | 5 | UniProt NCBI |
| ZNF354A | Zinc finger protein 354A (Transcription factor 17) (TCF-17) (Zinc finger protein eZNF) | 4 | UniProt NCBI |
| RPLP2 | Large ribosomal subunit protein P2 (60S acidic ribosomal protein P2) (Renal carcinoma antigen NY-REN-44) | 5 | UniProt NCBI |
| RPL13 | Large ribosomal subunit protein eL13 (60S ribosomal protein L13) (Breast basic conserved protein 1) | 5 | UniProt NCBI |
| RSBN1 | Lysine-specific demethylase 9 (KDM9) (EC 1.14.11.-) (Round spermatid basic protein 1) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:308 | 1.27203335103e-06 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | 60S ribosomal subunit, cytoplasmic |
| CORUM:306 | 1.22230677489e-05 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Ribosome, cytoplasmic |
| CORUM:5380 | 2.78062997571e-05 | 0.272727272727 | RPLP2 RPL34 RPL21 | TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) |
| REAC:R-HSA-6791226 | 3.0217850881e-05 | 0.454545454545 | RPLP2 NCL RPL21 RPL34 RPL27A | Major pathway of rRNA processing in the nucleolus and cytosol |
| CORUM:3055 | 3.11499140115e-05 | 0.363636363636 | RPLP2 NCL RPL21 RPL27A | Nop56p-associated pre-rRNA complex |
| WP:WP477 | 3.90846141078e-05 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Cytoplasmic ribosomal proteins |
| REAC:R-HSA-8868773 | 3.9578582275e-05 | 0.454545454545 | RPLP2 NCL RPL21 RPL34 RPL27A | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 5.1109611462e-05 | 0.454545454545 | RPLP2 NCL RPL21 RPL34 RPL27A | rRNA processing |
| KEGG:03010 | 9.57885741816e-05 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Ribosome |
| REAC:R-HSA-192823 | 0.000101582843612 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Viral mRNA Translation |
| REAC:R-HSA-156902 | 0.000101582843612 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Peptide chain elongation |
| REAC:R-HSA-72764 | 0.000116293768631 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.000116293768631 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Selenocysteine synthesis |
| REAC:R-HSA-156842 | 0.0001215330842 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Eukaryotic Translation Elongation |
| REAC:R-HSA-975956 | 0.000132537454108 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-9633012 | 0.000170031309032 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Response of EIF2AK4 (GCN2) to amino acid deficiency |
| REAC:R-HSA-72689 | 0.000170031309032 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Formation of a pool of free 40S subunits |
| REAC:R-HSA-1799339 | 0.000249373833558 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-156827 | 0.000249373833558 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-72706 | 0.000258596636738 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-2408522 | 0.000258596636738 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Selenoamino acid metabolism |
| REAC:R-HSA-927802 | 0.000287792570691 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-975957 | 0.000287792570691 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-72613 | 0.000330453220082 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Eukaryotic Translation Initiation |
| REAC:R-HSA-72737 | 0.000330453220082 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Cap-dependent Translation Initiation |
| REAC:R-HSA-168273 | 0.000502025334737 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Influenza Viral RNA Transcription and Replication |
| KEGG:05171 | 0.000552243892282 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Coronavirus disease - COVID-19 |
| REAC:R-HSA-168255 | 0.000816893159232 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Influenza Infection |
| REAC:R-HSA-9711097 | 0.000932462024328 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Cellular response to starvation |
| REAC:R-HSA-9824446 | 0.00117932968613 | 0.545454545455 | RPL34 RPLP2 RPL21 CNBP H2AC21 RPL27A | Viral Infection Pathways |
| REAC:R-HSA-9010553 | 0.00128965430728 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Regulation of expression of SLITs and ROBOs |
| GO:0002181 | 0.00226422666471 | 0.454545454545 | RPLP2 RPL27A RPL21 CNBP RPL34 | cytoplasmic translation |
| GO:0022625 | 0.00269387528282 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | cytosolic large ribosomal subunit |
| REAC:R-HSA-376176 | 0.00327241566306 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Signaling by ROBO receptors |
| REAC:R-HSA-5663205 | 0.00388433032282 | 0.545454545455 | RPL34 RPLP2 RPL21 CNBP H2AC21 RPL27A | Infectious disease |
| REAC:R-HSA-72766 | 0.0113197806384 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Translation |
| REAC:R-HSA-71291 | 0.017495396891 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | Metabolism of amino acids and derivatives |
| REAC:R-HSA-8953854 | 0.0209237584293 | 0.454545454545 | RPLP2 NCL RPL21 RPL34 RPL27A | Metabolism of RNA |
| GO:0006412 | 0.0467247091337 | 0.545454545455 | NCL RPL34 RPLP2 RPL21 CNBP RPL27A | translation |
| GO:0015934 | 0.0481291498767 | 0.363636363636 | RPLP2 RPL27A RPL34 RPL21 | large ribosomal subunit |
| CORUM:92 | 0.049976851631 | 0.0909090909091 | NCL | CD28-transactivation complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| RPL13 | RPL27A | 1.0 | 0.998 | |
| RPL27A | RPL21 | 1.0 | 1.0 | |
| RPL13 | RPL35A | 0.999 | 0.998 | |
| RPL34 | RPL27A | 0.999 | 0.996 | |
| RPL13 | RPLP2 | 0.999 | 0.968 | |
| RPL35A | RPL27A | 0.999 | 1.0 | |
| RPL13 | RPL34 | 0.999 | 0.998 | |
| RPL13 | RPL21 | 0.999 | 1.0 | |
| RPL27A | RPLP2 | 0.999 | 0.956 | |
| RPL35A | RPL34 | 0.997 | 0.994 | |
| RPL13 | NCL | 0.997 | 0.888 | |
| RPL34 | NCL | 0.996 | 0.504 | |
| NCL | RPL21 | 0.995 | 0.792 | |
| RPL35A | RPL21 | 0.994 | 1.0 | |
| RPL21 | RPLP2 | 0.994 | 0.96 | |
| RPL34 | H2AC21 | 0.994 | 0.160480519481 | |
| NCL | RPL27A | 0.993 | 0.787644444444 | |
| RPL34 | RPL21 | 0.992 | 0.998 | |
| RPL13 | H2AC21 | 0.992 | 0.496576271186 | |
| RPL35A | RPLP2 | 0.99 | 0.94 | |
| RPL35A | NCL | 0.985 | 0.412 | |
| CNBP | RPL34 | 0.981 | ||
| RPL34 | RPLP2 | 0.981 | 0.884 | |
| H2AC21 | RSBN1 | 0.98 | 0.086 | |
| MMTAG2 | RSBN1 | 0.98 | 0.056 | |
| RPL13 | MMTAG2 | 0.979 | 0.11 | |
| RPL21 | RSBN1 | 0.973 | 0.244 | |
| RPL13 | ZNF354A | 0.972 | ||
| RPL13 | RSBN1 | 0.971 | 0.502 | |
| RPL13 | ZFP62 | 0.971 | 0.188 | |
| MMTAG2 | RPL21 | 0.967 | 0.06 | |
| H2AC21 | RPLP2 | 0.966 | 0.227666666667 | |
| NCL | RPLP2 | 0.965 | 0.814 | |
| RPL34 | RSBN1 | 0.963 | 0.164 | |
| CNBP | RPL13 | 0.962 | ||
| RPL34 | MMTAG2 | 0.962 | 0.09 | |
| MMTAG2 | RPLP2 | 0.936 | 0.066 | |
| RPL35A | H2AC21 | 0.933 | 0.198 | |
| H2AC21 | RPL21 | 0.93 | 0.37 | |
| CNBP | RPL35A | 0.894 | ||
| MMTAG2 | RPL27A | 0.886 | 0.1 | |
| MMTAG2 | H2AC21 | 0.886 | 0.058 | |
| MMTAG2 | NCL | 0.877 | 0.038 | |
| RPL35A | MMTAG2 | 0.853 | 0.148 | |
| CNBP | RPL27A | 0.852 | ||
| NCL | H2AC21 | 0.845 | 0.215085245902 | |
| CNBP | RPL21 | 0.844 | ||
| CNBP | RPLP2 | 0.841 | ||
| RPL27A | H2AC21 | 0.799 | 0.22 | |
| RPL34 | ZNF354A | 0.732 | ||
| CNBP | NCL | 0.721 | ||
| ZFP62 | ZNF354A | 0.708 | ||
| ZFP62 | H2AC21 | 0.706 | 0.134 | |
| RPL35A | ZNF354A | 0.703 | ||
| ZFP62 | RPL34 | 0.637 | 0.156 | |
| RPL35A | RSBN1 | 0.608 | 0.216 | |
| RPLP2 | RSBN1 | 0.604 | 0.18 | |
| RPL27A | RSBN1 | 0.587 | 0.25 | |
| ZFP62 | MMTAG2 | 0.57 | 0.056 | |
| NCL | RSBN1 | 0.537 | 0.224 | |
| NCL | ZNF354A | 0.525 | ||
| ZFP62 | RPL21 | 0.521 | 0.156 | |
| H2AC21 | ZNF354A | 0.518 | ||
| RPL35A | ZFP62 | 0.51 | 0.23 | |
| ZNF354A | RPLP2 | 0.479 | ||
| RPL21 | ZNF354A | 0.479 | ||
| RPL27A | ZNF354A | 0.466 | ||
| CNBP | ZFP62 | 0.456 | ||
| ZFP62 | RPLP2 | 0.431 | 0.118 | |
| ZNF354A | RSBN1 | 0.412 | ||
| ZFP62 | RPL27A | 0.383 | 0.192 | |
| ZFP62 | RSBN1 | 0.371 | 0.088 | |
| ZFP62 | NCL | 0.365 | 0.12 | |
| MMTAG2 | ZNF354A | 0.206 | ||
| CNBP | MMTAG2 | 0.035 |
Related Complexes
| Genename | Complexes |
|---|---|
| RPL35A | huMAP3_03610.1 |
| CNBP | huMAP3_01224.1 huMAP3_03610.1 huMAP3_05807.1 huMAP3_05878.1 huMAP3_07662.1 huMAP3_09815.1 huMAP3_10406.1 huMAP3_11549.1 |
| ZFP62 | huMAP3_03610.1 huMAP3_04381.1 huMAP3_05038.1 huMAP3_05807.1 huMAP3_08334.1 huMAP3_10445.1 huMAP3_10756.1 |
| RPL34 | huMAP3_03610.1 huMAP3_05807.1 |
| MMTAG2 | huMAP3_03610.1 huMAP3_05807.1 |
| NCL | huMAP3_03610.1 |
| RPL27A | huMAP3_03610.1 |
| H2AC21 | huMAP3_03610.1 huMAP3_05807.1 |
| RPL21 | huMAP3_03610.1 |
| ZNF354A | huMAP3_03610.1 huMAP3_05038.1 huMAP3_05807.1 huMAP3_06161.1 huMAP3_08334.1 huMAP3_10756.1 |
| RPLP2 | huMAP3_03610.1 |
| RPL13 | huMAP3_01875.1 huMAP3_03610.1 huMAP3_05807.1 huMAP3_07487.1 huMAP3_08315.1 |
| RSBN1 | huMAP3_03610.1 |