hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03621.1
Complex Portal: CPX-20254
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GUCY2D | Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (CG-E) (Guanylate cyclase 2D, retinal) (Rod outer segment membrane guanylate cyclase) (ROS-GC) | 5 | UniProt NCBI |
| MXRA7 | Matrix-remodeling-associated protein 7 | 3 | UniProt NCBI |
| GUCY2F | Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04744 | 0.000103747375292 | 0.666666666667 | GUCY2D GUCY2F | Phototransduction |
| REAC:R-HSA-2514859 | 0.00172341693863 | 0.666666666667 | GUCY2D GUCY2F | Inactivation, recovery and regulation of the phototransduction cascade |
| REAC:R-HSA-2514856 | 0.00172341693863 | 0.666666666667 | GUCY2D GUCY2F | The phototransduction cascade |
| KEGG:00230 | 0.00361241039138 | 0.666666666667 | GUCY2D GUCY2F | Purine metabolism |
| GO:0007168 | 0.0140440992017 | 0.666666666667 | GUCY2D GUCY2F | receptor guanylyl cyclase signaling pathway |
| REAC:R-HSA-2187338 | 0.0204048321881 | 0.666666666667 | GUCY2D GUCY2F | Visual phototransduction |
| GO:0004383 | 0.0210651876021 | 0.666666666667 | GUCY2D GUCY2F | guanylate cyclase activity |
| GO:0006182 | 0.0294899169624 | 0.666666666667 | GUCY2D GUCY2F | cGMP biosynthetic process |
| GO:0022400 | 0.0393180950424 | 0.666666666667 | GUCY2D GUCY2F | regulation of rhodopsin mediated signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GUCY2D | GUCY2F | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GUCY2D | MXRA7 | 0.967 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GUCY2D | huMAP3_00856.1 huMAP3_03621.1 |
| MXRA7 | huMAP3_03621.1 huMAP3_09985.1 huMAP3_11561.1 huMAP3_13737.1 huMAP3_14355.1 |
| GUCY2F | huMAP3_00856.1 huMAP3_03621.1 |