List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_03628.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
COPS9	COP9 signalosome complex subunit 9 (CSN acidic protein) (CSNAP) (Myeloma-overexpressed gene 2 protein)	5	UniProt   NCBI
DCAF16	DDB1- and CUL4-associated factor 16	4	UniProt   NCBI
DCAF6	DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	5	UniProt   NCBI
BTBD1	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)	5	UniProt   NCBI
ERCC8	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)	5	UniProt   NCBI
FEM1C	Protein fem-1 homolog C (FEM1c) (FEM1-gamma)	5	UniProt   NCBI
ANKRD39	Ankyrin repeat domain-containing protein 39	2	UniProt   NCBI
LRR1	Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5)	5	UniProt   NCBI
GPS1	COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)	5	UniProt   NCBI
FEM1B	Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)	5	UniProt   NCBI
DCAF4	DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A)	5	UniProt   NCBI
BTBD2	BTB/POZ domain-containing protein 2	5	UniProt   NCBI
DCAF11	DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8951664	4.59619788851e-14	0.769230769231	FEM1B LRR1 DCAF4 BTBD1 DCAF16 ERCC8 DCAF11 DCAF6 FEM1C GPS1	Neddylation
REAC:R-HSA-597592	1.08001743465e-06	0.769230769231	FEM1B LRR1 DCAF4 BTBD1 DCAF16 ERCC8 DCAF11 DCAF6 FEM1C GPS1	Post-translational protein modification
GO:0031461	1.97539033477e-06	0.538461538462	DCAF11 DCAF4 FEM1B DCAF16 ERCC8 DCAF6 FEM1C	cullin-RING ubiquitin ligase complex
GO:0080008	4.30740859998e-06	0.384615384615	DCAF11 DCAF6 DCAF4 DCAF16 ERCC8	Cul4-RING E3 ubiquitin ligase complex
REAC:R-HSA-392499	2.5956925309e-05	0.769230769231	FEM1B LRR1 DCAF4 BTBD1 DCAF16 ERCC8 DCAF11 DCAF6 FEM1C GPS1	Metabolism of proteins
GO:0000151	6.50346160764e-05	0.538461538462	DCAF11 DCAF4 FEM1B DCAF16 ERCC8 DCAF6 FEM1C	ubiquitin ligase complex
CORUM:727	0.00269463984543	0.153846153846	ERCC8 GPS1	CSA complex
CORUM:728	0.00269463984543	0.153846153846	ERCC8 GPS1	CSA-POLIIa complex



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
LRR1	GPS1	1.0	0.19
GPS1	DCAF4	1.0	0.086
BTBD1	BTBD2	1.0	0.13
GPS1	BTBD2	0.999	0.312
BTBD1	GPS1	0.999	0.162
COPS9	GPS1	0.999	0.122
GPS1	DCAF11	0.999	0.158
LRR1	DCAF4	0.999	0.106
GPS1	FEM1B	0.999	0.124
DCAF4	DCAF11	0.999	0.048
ANKRD39	GPS1	0.995	0.106
BTBD1	LRR1	0.994	0.114
FEM1C	GPS1	0.994
DCAF6	GPS1	0.994	0.192
LRR1	BTBD2	0.991	0.08
LRR1	FEM1B	0.991	0.158
COPS9	BTBD2	0.991	0.176
ERCC8	GPS1	0.99	0.142
BTBD1	DCAF11	0.987	0.056
COPS9	DCAF11	0.986	0.068
BTBD1	DCAF4	0.985	0.078
COPS9	BTBD1	0.985	0.106
COPS9	LRR1	0.983	0.09
COPS9	FEM1B	0.981	0.1
DCAF16	DCAF6	0.98	0.054
COPS9	ERCC8	0.979	0.17
LRR1	DCAF11	0.979	0.106
BTBD1	FEM1B	0.977	0.158
DCAF16	GPS1	0.973	0.246
ERCC8	DCAF4	0.973	0.112
FEM1B	DCAF4	0.972	0.09
ERCC8	DCAF11	0.969	0.108
DCAF16	DCAF11	0.966	0.074
FEM1B	DCAF11	0.96	0.08
DCAF4	BTBD2	0.96	0.068
COPS9	DCAF4	0.951	0.102
DCAF6	DCAF11	0.938	0.06
FEM1B	BTBD2	0.936	0.154
FEM1C	FEM1B	0.884
ERCC8	FEM1B	0.815	0.094
ERCC8	LRR1	0.8	0.074
BTBD2	DCAF11	0.797	0.13
BTBD1	ERCC8	0.781	0.096
DCAF6	ERCC8	0.764	0.084
ANKRD39	BTBD2	0.73	0.136
ERCC8	BTBD2	0.725	0.154
FEM1C	DCAF4	0.565
FEM1C	LRR1	0.553
DCAF6	LRR1	0.522	0.076
DCAF6	DCAF4	0.508	0.1
DCAF16	ANKRD39	0.444	0.124
DCAF16	ERCC8	0.435	0.084
FEM1C	COPS9	0.401
ERCC8	ANKRD39	0.389	0.098
DCAF6	BTBD2	0.345	0.098
COPS9	DCAF6	0.311	0.078
FEM1C	DCAF11	0.283
DCAF6	FEM1B	0.282	0.14
FEM1C	BTBD1	0.244
FEM1C	DCAF6	0.239
DCAF6	BTBD1	0.233	0.108
DCAF16	FEM1C	0.165
ANKRD39	DCAF11	0.151	0.09
BTBD1	ANKRD39	0.146	0.114
DCAF16	DCAF4	0.114	0.076
FEM1C	ANKRD39	0.113
ANKRD39	DCAF4	0.102	0.12
FEM1C	BTBD2	0.101
ANKRD39	LRR1	0.076	0.12
FEM1C	ERCC8	0.076
ANKRD39	FEM1B	0.064	0.164
DCAF16	FEM1B	0.055	0.1
DCAF16	BTBD2	0.046	0.176
DCAF6	ANKRD39	0.046	0.138
DCAF16	LRR1	0.044	0.142
DCAF16	BTBD1	0.035	0.106
DCAF16	COPS9	0.026	0.09





Related Complexes

Genename	Complexes
COPS9	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
DCAF16	huMAP3_02953.1 huMAP3_03628.1 huMAP3_07590.1 huMAP3_08251.1 huMAP3_08550.1 huMAP3_09283.1 huMAP3_09779.1 huMAP3_10612.1 huMAP3_14528.1 huMAP3_14809.1
DCAF6	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09283.1 huMAP3_09779.1 huMAP3_10612.1 huMAP3_12773.1 huMAP3_14528.1
BTBD1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
ERCC8	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
FEM1C	huMAP3_03490.1 huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12267.1 huMAP3_13131.1 huMAP3_14528.1
ANKRD39	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
LRR1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_13769.1 huMAP3_14528.1
GPS1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
FEM1B	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12267.1 huMAP3_14528.1
DCAF4	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
BTBD2	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12609.1 huMAP3_14528.1
DCAF11	huMAP3_03628.1 huMAP3_06836.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1