hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03629.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARF3 | ADP-ribosylation factor 3 | 5 | UniProt NCBI |
| ARF5 | ADP-ribosylation factor 5 | 5 | UniProt NCBI |
| ARF4 | ADP-ribosylation factor 4 | 5 | UniProt NCBI |
| ARF1 | ADP-ribosylation factor 1 (EC 3.6.5.2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6811434 | 2.8038653175e-07 | 1.0 | ARF3 ARF1 ARF4 ARF5 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 3.19012801851e-07 | 1.0 | ARF3 ARF1 ARF4 ARF5 | COPI-mediated anterograde transport |
| REAC:R-HSA-8856688 | 9.61191287772e-07 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-199977 | 1.60388786364e-06 | 1.0 | ARF3 ARF1 ARF4 ARF5 | ER to Golgi Anterograde Transport |
| KEGG:04144 | 2.71547092057e-06 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Endocytosis |
| REAC:R-HSA-948021 | 3.38113611255e-06 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-6811442 | 5.38081396231e-06 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| REAC:R-HSA-446203 | 2.51247856948e-05 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Asparagine N-linked glycosylation |
| REAC:R-HSA-199991 | 0.000426838992032 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.000530772712934 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Vesicle-mediated transport |
| REAC:R-HSA-1660514 | 0.00122873738811 | 0.5 | ARF3 ARF1 | Synthesis of PIPs at the Golgi membrane |
| GO:0003924 | 0.00366770658506 | 1.0 | ARF3 ARF1 ARF4 ARF5 | GTPase activity |
| GO:0006890 | 0.00751763182363 | 0.75 | ARF3 ARF4 ARF5 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| REAC:R-HSA-597592 | 0.0091733555377 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Post-translational protein modification |
| WP:WP5224 | 0.0138131669346 | 0.5 | ARF5 ARF1 | 2q37 copy number variation syndrome |
| GO:0017111 | 0.0191409054275 | 1.0 | ARF3 ARF1 ARF4 ARF5 | ribonucleoside triphosphate phosphatase activity |
| REAC:R-HSA-1483255 | 0.0260384914588 | 0.5 | ARF3 ARF1 | PI Metabolism |
| GO:0016818 | 0.0305291540849 | 1.0 | ARF3 ARF1 ARF4 ARF5 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016817 | 0.0305291540849 | 1.0 | ARF3 ARF1 ARF4 ARF5 | hydrolase activity, acting on acid anhydrides |
| GO:0016462 | 0.0305291540849 | 1.0 | ARF3 ARF1 ARF4 ARF5 | pyrophosphatase activity |
| REAC:R-HSA-392499 | 0.0339333915692 | 1.0 | ARF3 ARF1 ARF4 ARF5 | Metabolism of proteins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARF5 | ARF1 | 0.998 | 0.296 | bioplex3_HEK293 Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction |
| ARF3 | ARF5 | 0.993 | 0.724 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
| ARF5 | ARF4 | 0.991 | 0.534 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
| ARF4 | ARF1 | 0.968 | 0.286 | Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| ARF3 | ARF1 | 0.878 | 0.312666666667 | bioplex3_WMM WMM_only boldt_WMM |
| ARF3 | ARF4 | 0.314 | 0.774 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ARF3 | huMAP3_03629.1 huMAP3_11827.1 huMAP3_12024.1 |
| ARF5 | huMAP3_03629.1 huMAP3_05921.1 huMAP3_12024.1 |
| ARF4 | huMAP3_03629.1 huMAP3_12024.1 |
| ARF1 | huMAP3_03629.1 huMAP3_12024.1 |