hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03654.1
Complex Portal: CPX-23191
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NIPA1 | Magnesium transporter NIPA1 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 1) (Spastic paraplegia 6 protein) | 5 | UniProt NCBI |
| SLC18B1 | MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) | 5 | UniProt NCBI |
| ABHD17C | Alpha/beta hydrolase domain-containing protein 17C (Abhydrolase domain-containing protein 17C) (EC 3.1.2.22) | 5 | UniProt NCBI |
| COA6 | Cytochrome c oxidase assembly factor 6 homolog | 5 | UniProt NCBI |
| CYSTM1 | Cysteine-rich and transmembrane domain-containing protein 1 | 3 | UniProt NCBI |
| ADCK1 | AarF domain-containing protein kinase 1 (EC 2.7.-.-) | 5 | UniProt NCBI |
| TMEM177 | Transmembrane protein 177 | 3 | UniProt NCBI |
| DOP1B | Protein dopey-2 | 5 | UniProt NCBI |
| MFSD4A | Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4) | 3 | UniProt NCBI |
| STARD3 | StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4922 | 0.0203472698002 | 0.2 | COA6 TMEM177 | Mitochondrial complex IV assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ABHD17C | MFSD4A | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DOP1B | MFSD4A | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NIPA1 | MFSD4A | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ADCK1 | MFSD4A | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CYSTM1 | MFSD4A | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC18B1 | MFSD4A | 0.988 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMEM177 | MFSD4A | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| COA6 | MFSD4A | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| MFSD4A | STARD3 | 0.959 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ADCK1 | STARD3 | 0.954 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEM177 | STARD3 | 0.941 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC18B1 | STARD3 | 0.927 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only | |
| ADCK1 | TMEM177 | 0.881 | 0.13 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABHD17C | TMEM177 | 0.805 | bioplex3_WMM WMM_only | ||
| NIPA1 | SLC18B1 | 0.797 | 0.152 | bioplex3_WMM WMM_only | |
| TMEM177 | DOP1B | 0.634 | 0.032 | bioplex3_WMM WMM_only | |
| NIPA1 | DOP1B | 0.634 | 0.048 | bioplex3_WMM WMM_only | |
| ABHD17C | DOP1B | 0.634 | bioplex3_WMM WMM_only | ||
| NIPA1 | STARD3 | 0.633 | 0.086 | bioplex3_WMM WMM_only | |
| ABHD17C | STARD3 | 0.621 | bioplex3_WMM WMM_only | ||
| ADCK1 | DOP1B | 0.604 | 0.066 | bioplex3_WMM WMM_only | |
| ADCK1 | SLC18B1 | 0.592 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ADCK1 | COA6 | 0.416 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABHD17C | ADCK1 | 0.41 | bioplex3_WMM WMM_only | ||
| TMEM177 | NIPA1 | 0.392 | 0.11 | bioplex3_WMM WMM_only | |
| ADCK1 | NIPA1 | 0.363 | 0.144 | bioplex3_WMM WMM_only | |
| DOP1B | STARD3 | 0.348 | 0.06 | bioplex3_WMM WMM_only | |
| ABHD17C | SLC18B1 | 0.267 | bioplex3_WMM WMM_only | ||
| ABHD17C | NIPA1 | 0.255 | bioplex3_WMM WMM_only | ||
| SLC18B1 | DOP1B | 0.249 | 0.07 | bioplex3_WMM WMM_only | |
| TMEM177 | SLC18B1 | 0.246 | 0.04 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| COA6 | SLC18B1 | 0.246 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABHD17C | COA6 | 0.181 | bioplex3_WMM WMM_only | ||
| COA6 | NIPA1 | 0.18 | 0.058 | bioplex3_WMM WMM_only | |
| COA6 | DOP1B | 0.144 | 0.01 | bioplex3_WMM WMM_only | |
| TMEM177 | COA6 | 0.108 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only | |
| COA6 | CYSTM1 | 0.089 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| COA6 | STARD3 | 0.086 | 0.02 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEM177 | CYSTM1 | 0.075 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| ABHD17C | CYSTM1 | 0.046 | bioplex3_WMM WMM_only | ||
| CYSTM1 | DOP1B | 0.042 | 0.054 | bioplex3_WMM WMM_only | |
| NIPA1 | CYSTM1 | 0.042 | 0.084 | bioplex3_WMM WMM_only | |
| ADCK1 | CYSTM1 | 0.026 | 0.078 | bioplex3_WMM WMM_only | |
| SLC18B1 | CYSTM1 | 0.026 | 0.114 | bioplex3_WMM WMM_only | |
| CYSTM1 | STARD3 | 0.026 | 0.05 | bioplex3_WMM WMM_only |
Related Complexes