hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03684.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPATA46 | Spermatogenesis-associated protein 46 | 4 | UniProt NCBI |
| HLCS | Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00780 | 0.00712689283602 | 0.5 | HLCS | Biotin metabolism |
| HP:0011127 | 0.0499436884913 | 0.5 | HLCS | Perioral eczema |
| HP:4000200 | 0.0499436884913 | 0.5 | HLCS | Reduced holocarboxylase synthetase activity in cultured fibroblasts |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HLCS | SPATA46 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| SPATA46 | huMAP3_03684.1 huMAP3_06191.1 huMAP3_07204.1 |
| HLCS | huMAP3_03426.1 huMAP3_03684.1 huMAP3_12533.1 huMAP3_14363.1 huMAP3_14381.1 |