hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03716.1
Complex Portal: CPX-11835
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TNIK | TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1) | 5 | UniProt NCBI |
| MINK1 | Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4537 | 7.2783930122e-05 | 1.0 | TNIK MINK1 | Hippo YAP signaling |
| REAC:R-HSA-2559580 | 0.00969038789632 | 1.0 | TNIK MINK1 | Oxidative Stress Induced Senescence |
| REAC:R-HSA-2559583 | 0.0260158976762 | 1.0 | TNIK MINK1 | Cellular Senescence |
| WP:WP5087 | 0.0293715080819 | 1.0 | TNIK MINK1 | Pleural mesothelioma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MINK1 | TNIK | 0.996 | 0.14 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TNIK | huMAP3_03716.1 huMAP3_08747.1 huMAP3_09119.1 huMAP3_09757.1 |
| MINK1 | huMAP3_00935.1 huMAP3_03716.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_09757.1 huMAP3_10333.1 |