hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03750.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FURIN | Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) | 5 | UniProt NCBI |
| SERPINI1 | Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1) | 5 | UniProt NCBI |
| PXYLP1 | 2-phosphoxylose phosphatase 1 (EC 3.1.3.-) (Acid phosphatase-like protein 2) (Xylosyl phosphatase) (epididymis luminal protein 124) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5065 | 0.0331010360575 | 0.333333333333 | FURIN | SARS CoV 2 altering angiogenesis via NRP1 |
| WP:WP4846 | 0.0496447587094 | 0.333333333333 | FURIN | SARS CoV 2 and COVID 19 pathway |
| REAC:R-HSA-171286 | 0.0498224659464 | 0.333333333333 | FURIN | Synthesis and processing of ENV and VPU |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PXYLP1 | FURIN | 0.997 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| FURIN | SERPINI1 | 0.989 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PXYLP1 | SERPINI1 | 0.652 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| FURIN | huMAP3_03750.1 huMAP3_14312.1 |
| SERPINI1 | huMAP3_03750.1 huMAP3_12328.1 huMAP3_13595.1 huMAP3_14312.1 huMAP3_14699.1 |
| PXYLP1 | huMAP3_00529.1 huMAP3_03750.1 huMAP3_10818.1 huMAP3_11112.1 |