hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03764.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CALML5 | Calmodulin-like protein 5 (Calmodulin-like skin protein) | 5 | UniProt NCBI |
| S100A11 | Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed] | 5 | UniProt NCBI |
| S100A7A | Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A) | 5 | UniProt NCBI |
| S100A8 | Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A) | 5 | UniProt NCBI |
| KIR3DS1 | Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6799990 | 0.000153732433522 | 0.5 | S100A7A S100A8 | Metal sequestration by antimicrobial proteins |
| REAC:R-HSA-168249 | 0.00247124639724 | 1.0 | CALML5 S100A8 S100A11 S100A7A | Innate Immune System |
| GO:0005509 | 0.00728390316897 | 1.0 | CALML5 S100A8 S100A11 S100A7A | calcium ion binding |
| KEGG:04657 | 0.00728891894502 | 0.5 | S100A7A S100A8 | IL-17 signaling pathway |
| GO:0048306 | 0.0112187083505 | 0.75 | S100A7A S100A11 S100A8 | calcium-dependent protein binding |
| HPA:0470182 | 0.0137538378506 | 0.75 | CALML5 S100A11 S100A8 | skin 2; cells in granular layer[>=Medium] |
| REAC:R-HSA-6803157 | 0.0162811003561 | 0.5 | S100A7A S100A8 | Antimicrobial peptides |
| REAC:R-HSA-6798695 | 0.0179349264259 | 0.75 | CALML5 S100A11 S100A8 | Neutrophil degranulation |
| HPA:0471412 | 0.025307719873 | 0.75 | CALML5 S100A11 S100A8 | skin 2; cells in spinous layer[>=Medium] |
| HPA:0470181 | 0.0287284084928 | 0.75 | CALML5 S100A11 S100A8 | skin 2; cells in granular layer[>=Low] |
| REAC:R-HSA-168256 | 0.032293648674 | 1.0 | CALML5 S100A8 S100A11 S100A7A | Immune System |
| HPA:0471442 | 0.0454353332194 | 0.75 | CALML5 S100A11 S100A8 | skin 2; fibrohistiocytic cells[>=Medium] |
| CORUM:6826 | 0.049938562206 | 0.25 | S100A8 | Calprotectin heterotetramer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| S100A8 | CALML5 | 0.981 | 0.176086956522 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM treiber_WMM WMM_only |
| KIR3DS1 | CALML5 | 0.974 | bioplex3_HEK293 bioplex () | |
| S100A11 | CALML5 | 0.973 | 0.202 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| CALML5 | S100A7A | 0.966 | bioplex_WMM bioplex3_WMM WMM_only | |
| S100A8 | S100A7A | 0.962 | bioplex_WMM bioplex3_WMM WMM_only | |
| KIR3DS1 | S100A8 | 0.952 | bioplex3_HEK293 bioplex () | |
| S100A11 | S100A8 | 0.543 | 0.218 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only |
| S100A11 | S100A7A | 0.29 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes