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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_03767.1
Complex Portal:
CPX-18485
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
CAPN1
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
5
UniProt
NCBI
CAPN2
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)
5
UniProt
NCBI
CAPNS1
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
CORUM:6710
1.70876175213e-06
1.0
CAPN1 CAPNS1
Calpain 1
REAC:R-HSA-8862803
0.000358839967947
1.0
CAPN1 CAPNS1
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
REAC:R-HSA-8863678
0.000358839967947
1.0
CAPN1 CAPNS1
Neurodegenerative Diseases
REAC:R-HSA-9734009
0.000471618243588
1.0
CAPN1 CAPNS1
Defective Intrinsic Pathway for Apoptosis
WP:WP185
0.00148377064565
1.0
CAPN1 CAPNS1
Integrin mediated cell adhesion
GO:0110158
0.0028092043205
1.0
CAPN1 CAPNS1
calpain complex
REAC:R-HSA-6809371
0.00377807223396
1.0
CAPN1 CAPNS1
Formation of the cornified envelope
REAC:R-HSA-6805567
0.00400875507049
1.0
CAPN1 CAPNS1
Keratinization
KEGG:05131
0.00417007523294
1.0
CAPN1 CAPNS1
Shigellosis
REAC:R-HSA-9645723
0.00699737937497
1.0
CAPN1 CAPNS1
Diseases of programmed cell death
Showing 1 to 10 of 16 entries
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
CAPN1
CAPNS1
1.0
0.604
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
CAPN2
CAPNS1
0.987
0.336
mutually_exclusive (Q96L46)
structurally_consistent (dimer)
bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
CAPN2
CAPN1
0.963
0.16
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
CAPN1
huMAP3_03767.1
huMAP3_08670.1
huMAP3_09127.1
huMAP3_09328.1
huMAP3_10242.1
huMAP3_11557.1
huMAP3_12716.1
huMAP3_12926.1
huMAP3_13615.1
huMAP3_14229.1
CAPNS1
huMAP3_03767.1
huMAP3_08081.1
huMAP3_08670.1
huMAP3_09127.1
huMAP3_09328.1
huMAP3_10242.1
huMAP3_11557.1
huMAP3_12239.1
huMAP3_12453.1
huMAP3_12716.1
huMAP3_12926.1
huMAP3_13615.1
huMAP3_14229.1
huMAP3_15135.1
CAPN2
huMAP3_03420.1
huMAP3_03767.1
huMAP3_08081.1
huMAP3_08670.1
huMAP3_09127.1
huMAP3_09328.1
huMAP3_10029.1
huMAP3_10242.1
huMAP3_11160.1
huMAP3_11557.1
huMAP3_12453.1
huMAP3_12716.1
huMAP3_12926.1
huMAP3_13615.1
huMAP3_14229.1