hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03785.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NKD1 | Protein naked cuticle homolog 1 (Naked-1) (hNkd) (hNkd1) | 5 | UniProt NCBI |
| PRICKLE1 | Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1) | 5 | UniProt NCBI |
| ROBO1 | Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) | 5 | UniProt NCBI |
| MOV10L1 | RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1) | 5 | UniProt NCBI |
| ANKIB1 | Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31) | 5 | UniProt NCBI |
| CDCA7 | Cell division cycle-associated protein 7 (Protein JPO1) | 5 | UniProt NCBI |
| NRSN2 | Neurensin-2 | 3 | UniProt NCBI |
| KCNE3 | Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2) | 5 | UniProt NCBI |
| RNF125 | E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1) | 5 | UniProt NCBI |
| NBEAL1 | Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein) | 3 | UniProt NCBI |
| DACT1 | Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein) | 5 | UniProt NCBI |
| MERTK | Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK) | 5 | UniProt NCBI |
| RND2 | Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2) | 5 | UniProt NCBI |
| PRICKLE2 | Prickle-like protein 2 | 4 | UniProt NCBI |
| CAPN15 | Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0060071 | 0.00184578702363 | 0.266666666667 | NKD1 PRICKLE2 DACT1 PRICKLE1 | Wnt signaling pathway, planar cell polarity pathway |
| GO:0035567 | 0.0110213858614 | 0.266666666667 | NKD1 PRICKLE2 DACT1 PRICKLE1 | non-canonical Wnt signaling pathway |
| WP:WP428 | 0.0152467942057 | 0.2 | NKD1 PRICKLE2 PRICKLE1 | Wnt signaling |
| KEGG:04310 | 0.0251097280425 | 0.2 | NKD1 PRICKLE2 PRICKLE1 | Wnt signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| PRICKLE1 | KCNE3 | 0.999 | |
| KCNE3 | CAPN15 | 0.999 | |
| ANKIB1 | KCNE3 | 0.999 | |
| KCNE3 | NBEAL1 | 0.998 | |
| MOV10L1 | KCNE3 | 0.997 | |
| KCNE3 | PRICKLE2 | 0.988 | |
| CDCA7 | KCNE3 | 0.988 | |
| KCNE3 | RND2 | 0.988 | |
| KCNE3 | RNF125 | 0.986 | |
| NKD1 | KCNE3 | 0.986 | |
| NRSN2 | KCNE3 | 0.98 | |
| KCNE3 | DACT1 | 0.972 | |
| KCNE3 | MERTK | 0.956 | |
| ROBO1 | KCNE3 | 0.951 | |
| PRICKLE1 | CAPN15 | 0.916 | |
| PRICKLE1 | MOV10L1 | 0.902 | |
| MOV10L1 | ANKIB1 | 0.902 | |
| ANKIB1 | CAPN15 | 0.902 | 0.094 |
| PRICKLE1 | NBEAL1 | 0.902 | |
| PRICKLE1 | ANKIB1 | 0.902 | |
| ANKIB1 | NBEAL1 | 0.902 | 0.046 |
| MOV10L1 | NBEAL1 | 0.902 | |
| MOV10L1 | CAPN15 | 0.892 | |
| NBEAL1 | CAPN15 | 0.755 | 0.062 |
| CDCA7 | PRICKLE2 | 0.415 | |
| NKD1 | RND2 | 0.415 | |
| PRICKLE1 | PRICKLE2 | 0.415 | |
| RNF125 | MERTK | 0.415 | |
| RNF125 | DACT1 | 0.415 | |
| RNF125 | RND2 | 0.415 | |
| DACT1 | RND2 | 0.415 | |
| NKD1 | PRICKLE2 | 0.415 | |
| CDCA7 | RND2 | 0.415 | |
| CDCA7 | DACT1 | 0.415 | |
| PRICKLE1 | RNF125 | 0.415 | |
| RND2 | PRICKLE2 | 0.415 | |
| DACT1 | PRICKLE2 | 0.415 | |
| PRICKLE1 | RND2 | 0.415 | |
| NKD1 | DACT1 | 0.415 | |
| CDCA7 | RNF125 | 0.415 | |
| NKD1 | MERTK | 0.415 | |
| NKD1 | PRICKLE1 | 0.415 | |
| MERTK | PRICKLE2 | 0.415 | |
| PRICKLE1 | MERTK | 0.415 | |
| NKD1 | RNF125 | 0.415 | |
| PRICKLE1 | CDCA7 | 0.415 | |
| PRICKLE1 | DACT1 | 0.415 | |
| NKD1 | CDCA7 | 0.415 | |
| RNF125 | PRICKLE2 | 0.415 | |
| DACT1 | MERTK | 0.415 | |
| PRICKLE2 | CAPN15 | 0.364 | |
| RNF125 | CAPN15 | 0.364 | |
| NKD1 | CAPN15 | 0.364 | |
| ROBO1 | RNF125 | 0.278 | |
| ROBO1 | PRICKLE2 | 0.278 | |
| PRICKLE1 | ROBO1 | 0.278 | |
| NKD1 | ROBO1 | 0.278 | |
| NKD1 | NRSN2 | 0.274 | |
| MERTK | RND2 | 0.274 | |
| CDCA7 | MERTK | 0.274 | 0.082 |
| NRSN2 | RNF125 | 0.274 | |
| NRSN2 | PRICKLE2 | 0.274 | |
| PRICKLE1 | NRSN2 | 0.274 | |
| DACT1 | CAPN15 | 0.229 | |
| CDCA7 | NBEAL1 | 0.214 | 0.06 |
| RNF125 | NBEAL1 | 0.214 | |
| MOV10L1 | CDCA7 | 0.214 | |
| NBEAL1 | PRICKLE2 | 0.214 | |
| MOV10L1 | RNF125 | 0.214 | |
| ANKIB1 | DACT1 | 0.214 | |
| ANKIB1 | PRICKLE2 | 0.214 | |
| ANKIB1 | MERTK | 0.214 | 0.126 |
| NKD1 | ANKIB1 | 0.214 | |
| MOV10L1 | PRICKLE2 | 0.214 | |
| ANKIB1 | RND2 | 0.214 | |
| NKD1 | MOV10L1 | 0.214 | |
| NBEAL1 | DACT1 | 0.214 | |
| MOV10L1 | RND2 | 0.214 | |
| ANKIB1 | CDCA7 | 0.214 | 0.08 |
| MOV10L1 | MERTK | 0.214 | |
| ANKIB1 | RNF125 | 0.214 | |
| NKD1 | NBEAL1 | 0.214 | |
| NBEAL1 | RND2 | 0.214 | |
| MOV10L1 | DACT1 | 0.214 | |
| NBEAL1 | MERTK | 0.146 | 0.084 |
| ROBO1 | ANKIB1 | 0.146 | 0.092 |
| ANKIB1 | NRSN2 | 0.146 | 0.08 |
| NRSN2 | DACT1 | 0.113 | |
| ROBO1 | DACT1 | 0.113 | |
| ROBO1 | CDCA7 | 0.095 | 0.104 |
| ROBO1 | RND2 | 0.095 | |
| ROBO1 | CAPN15 | 0.095 | 0.092 |
| ROBO1 | NRSN2 | 0.087 | 0.094 |
| CDCA7 | CAPN15 | 0.083 | 0.062 |
| RND2 | CAPN15 | 0.083 | |
| ROBO1 | MERTK | 0.079 | 0.07 |
| NRSN2 | CAPN15 | 0.078 | 0.082 |
| NRSN2 | RND2 | 0.078 | |
| CDCA7 | NRSN2 | 0.078 | 0.052 |
| NRSN2 | MERTK | 0.076 | 0.044 |
| MERTK | CAPN15 | 0.07 | 0.106 |
| MOV10L1 | NRSN2 | 0.055 | |
| ROBO1 | MOV10L1 | 0.055 | |
| ROBO1 | NBEAL1 | 0.046 | 0.08 |
| NRSN2 | NBEAL1 | 0.043 | 0.062 |
Related Complexes