hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03787.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NOL9 | Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.78) (Nucleolar protein 9) | 5 | UniProt NCBI |
| SENP3 | Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3) | 5 | UniProt NCBI |
| WDR18 | WD repeat-containing protein 18 | 5 | UniProt NCBI |
| LAS1L | Ribosomal biogenesis protein LAS1L (Endoribonuclease LAS1L) (EC 3.1.-.-) (Protein LAS1 homolog) | 5 | UniProt NCBI |
| NAP1L1 | Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6855 | 5.7528607006e-12 | 0.8 | SENP3 LAS1L NOL9 WDR18 | LAS1L-PELP1-TEX10-WDR18-NOL9-SENP3 complex |
| CORUM:6854 | 2.80175822576e-08 | 0.6 | SENP3 WDR18 LAS1L | 5FMC (Friends of Methylated Chtop) complex |
| REAC:R-HSA-6791226 | 1.78931053685e-05 | 0.8 | SENP3 LAS1L NOL9 WDR18 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 2.22403493572e-05 | 0.8 | SENP3 LAS1L NOL9 WDR18 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 2.73338576937e-05 | 0.8 | SENP3 LAS1L NOL9 WDR18 | rRNA processing |
| REAC:R-HSA-8953854 | 0.00371793814615 | 0.8 | SENP3 LAS1L NOL9 WDR18 | Metabolism of RNA |
| CORUM:5386 | 0.00442174926056 | 0.4 | SENP3 LAS1L | MLL1-WDR5 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SENP3 | WDR18 | 1.0 | 0.238 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction |
| NOL9 | WDR18 | 1.0 | 0.94 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction treiber_WMM |
| NOL9 | LAS1L | 1.0 | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| WDR18 | LAS1L | 1.0 | 0.86 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction treiber_WMM |
| SENP3 | NOL9 | 1.0 | 0.392 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| SENP3 | LAS1L | 0.999 | 0.586 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
| NOL9 | NAP1L1 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| SENP3 | NAP1L1 | 0.969 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only | |
| LAS1L | NAP1L1 | 0.943 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM | |
| WDR18 | NAP1L1 | 0.317 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
Related Complexes