hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03814.1
Complex Portal: CPX-20817
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMTC4 | Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 4) (Transmembrane and tetratricopeptide repeat-containing 4) | 5 | UniProt NCBI |
| CD79B | B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b) | 5 | UniProt NCBI |
| CYBC1 | Cytochrome b-245 chaperone 1 (Essential for reactive oxygen species protein) (Eros) | 5 | UniProt NCBI |
| NF1 | Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0032252 | 0.000501460556964 | 0.5 | CYBC1 NF1 | Granuloma |
| HP:0000246 | 0.00166488812958 | 0.75 | NF1 CD79B CYBC1 | Sinusitis |
| HP:0000245 | 0.00235645810497 | 0.75 | NF1 CD79B CYBC1 | Abnormal paranasal sinus morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CYBC1 | CD79B | 0.972 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NF1 | CD79B | 0.968 | 0.172 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TMTC4 | CD79B | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NF1 | TMTC4 | 0.243 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CYBC1 | NF1 | 0.158 | 0.018 | bioplex_WMM bioplex3_WMM WMM_only | |
| CYBC1 | TMTC4 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes