hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03827.1
Complex Portal: CPX-15800
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NANS | Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase) | 5 | UniProt NCBI |
| TMEM147 | BOS complex subunit TMEM147 (Protein NIFIE 14) (Transmembrane protein 147) | 5 | UniProt NCBI |
| USP30 | Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) | 5 | UniProt NCBI |
| PACC1 | Proton-activated chloride channel (PAC) (hPAC) (Acid-sensitive outwardly-rectifying anion channel) (ASOR) (Proton-activated outwardly rectifying anion channel) (PAORAC) (Transmembrane protein 206) (hTMEM206) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0034295 | 0.0145105245688 | 0.5 | TMEM147 NANS | Reduced cerebral white matter volume |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TMEM147 | PACC1 | 0.998 | 0.128 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| USP30 | PACC1 | 0.975 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NANS | PACC1 | 0.959 | 0.044 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TMEM147 | NANS | 0.885 | 0.046 | bioplex3_WMM WMM_only | |
| TMEM147 | USP30 | 0.154 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| USP30 | NANS | 0.03 | 0.121 | bioplex3_WMM WMM_only |
Related Complexes