hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03828.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAN2B1 | Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide] | 5 | UniProt NCBI |
| IDO1 | Indoleamine 2,3-dioxygenase 1 (IDO-1) (EC 1.13.11.52) (Indoleamine-pyrrole 2,3-dioxygenase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00511 | 0.0273048944826 | 1.0 | MAN2B1 | Other glycan degradation |
| HP:0007232 | 0.0495817777049 | 1.0 | MAN2B1 | Spinocerebellar tract disease in lower limbs |
| HP:0034712 | 0.0495817777049 | 1.0 | MAN2B1 | Decreased circulating alpha-mannosidase activity |
| HP:4000190 | 0.0495817777049 | 1.0 | MAN2B1 | Reduced leukocyte alpha-mannosidase activity |
| HP:4000201 | 0.0495817777049 | 1.0 | MAN2B1 | Abnormal circulating alpha mannosidase activity |
| REAC:R-HSA-8853383 | 0.0499436884912 | 1.0 | MAN2B1 | Lysosomal oligosaccharide catabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAN2B1 | IDO1 | 0.972 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MAN2B1 | huMAP3_03828.1 huMAP3_05774.1 huMAP3_14233.1 |
| IDO1 | huMAP3_03828.1 huMAP3_12408.1 huMAP3_13807.1 huMAP3_14233.1 |